Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 4/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26003240 | 0.88 | TAAR1 (0.41) | KCNN4KIF11TAAR1 | |
| SCHEMBL4077009 | 0.80 | KIF11 (0.41) | KCNN4KIF11LMNATAAR1GRIN1 | |
| SCHEMBL9579235 | 0.79 | RIPK1 (0.42) | KCNN4KIF11TAAR1MEN1KMT2A | |
| SCHEMBL6552391 | 0.78 | MEN1 (0.42) | LMNAMEN1KMT2AGRIN1GRIN2A | |
| SCHEMBL4454908 | 0.77 | GRIN1 (0.43) | KCNN4KIF11LMNATAAR1MEN1 | |
| SCHEMBL756001 | 0.77 | LMNA (0.42) | KCNN4LMNAMEN1KMT2AGRIN1 | |
| Ammonia Solution, Strong SCHEMBL9711079 | 0.77 | GRIN1 (0.47) | KCNN4KIF11LMNAGRIN1GRIN2A | |
| SCHEMBL9064416 | 0.76 | TAAR1 (0.40) | KCNN4KIF11LMNATAAR1MEN1 | |
| SCHEMBL28132136 | 0.73 | KCNN4 (0.44) | KCNN4KIF11LMNATAAR1MEN1 | |
| SCHEMBL5476175 | 0.72 | TAAR1 (0.38) | KCNN4KIF11LMNATAAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485106-A2 | PHOSPHONATE-PHOSPHATE AND DIPHOSPHONATE APOLIPOPROTEIN E MODULATORS | Ilex Products, Inc. (US) | 2004-12-15 | — | — | EP | claimed |
| WO-2003070179-A2 | PHOSPHONATE-PHOSPHATE AND DIPHOSPHONATE APOLIPOPROTEIN E MODULATORS | ILEX PRODUCTS, INC. (US) | 2003-08-28 | — | — | WO | claimed |