Sebacic Acid

Sebacic Acid

SCHEMBL6552430

C/C=C\C.O=C(O)CCCCCCCCC(=O)O

nearest known ligand 0.71

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.71
LMNA P02545 2/20 0.71
NFKB1 P19838 1/20 0.71
PMP22 Q01453 1/20 0.71
GPR84 Q9NQS5 8/20 0.62
PPARG P37231 7/20 0.62
PPARD Q03181 7/20 0.62
PPARA Q07869 7/20 0.62
HDAC11 Q96DB2 5/20 0.62
PTPN1 P18031 3/20 0.62
ALDH1A1 P00352 2/20 0.62
TLR2 O60603 2/20 0.62
TDP1 Q9NUW8 2/20 0.62
FABP4 P15090 2/20 0.62
FFAR1 O14842 2/20 0.62
FFAR4 Q5NUL3 2/20 0.62
SLC22A6 Q4U2R8 2/20 0.62
SLC22A8 Q8TCC7 1/20 0.62
MEN1 O00255 1/20 0.62
ESR1 P03372 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sebacic Acid SCHEMBL6551847 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22GPR84
Sebacic Acid SCHEMBL6551861 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22GPR84
Adipic Acid SCHEMBL6550913 0.97 LMNA (0.69) TSHRLMNANFKB1PMP22GPR84
Adipic Acid SCHEMBL6552701 0.97 LMNA (0.69) TSHRLMNANFKB1PMP22GPR84
Adipic Acid SCHEMBL6550920 0.97 LMNA (0.69) TSHRLMNANFKB1PMP22GPR84
Glutarate SCHEMBL3883818 0.91 SLC22A6 (0.69) TSHRLMNANFKB1PMP22GPR84
Sebacic Acid SCHEMBL28243888 0.91 TSHR (0.75) TSHRLMNANFKB1PMP22GPR84
Stearic Acid SCHEMBL27819323 0.90 GPR84 (0.81) TSHRLMNAGPR84PPARGPPARD
Propene SCHEMBL7054981 0.86 TSHR (0.67) TSHRLMNANFKB1PMP22GPR84
Propene SCHEMBL7052579 0.86 TSHR (0.67) TSHRLMNANFKB1PMP22GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786492-B1 Method for disposal of a plastic molded product MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2004-12-15 EP disclosed
US-5874482-A IMMERSING SAID THERMOSET PLASTIC MOLDED PRODUCT IN AN ALKALINE AQUEOUS SOLUTION TO PROMOTE PERMEATION AND PENETRATION OF SAID ALKALINE AQUEOUS SOLUTION INTO SAID THERMOSET PLASTIC MOLDED PRODUCT, CAUSING SOFTENING, WEAKENING MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1999-02-23 US disclosed
EP-0786492-A2 Plastic molded product and method for disposal of the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1997-07-30 EP disclosed