Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 5/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.60 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.59 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.57 |
| ▸ | PPARG | P37231 | 7/20 | 0.57 |
| ▸ | PPARD | Q03181 | 7/20 | 0.57 |
| ▸ | PPARA | Q07869 | 7/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TLR2 | O60603 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | FABP4 | P15090 | 2/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.57 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL6550913 | 1.00 | LMNA (0.69) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Adipic Acid SCHEMBL6550920 | 1.00 | LMNA (0.69) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Sebacic Acid SCHEMBL6551847 | 0.97 | TSHR (0.71) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Sebacic Acid SCHEMBL6551861 | 0.97 | TSHR (0.71) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Sebacic Acid SCHEMBL6552430 | 0.97 | TSHR (0.71) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Glutarate SCHEMBL3883818 | 0.94 | SLC22A6 (0.69) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Sebacic Acid SCHEMBL28243888 | 0.88 | TSHR (0.75) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Adipic Acid SCHEMBL749775 | 0.88 | LMNA (0.69) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Stearic Acid SCHEMBL27819323 | 0.87 | GPR84 (0.81) | LMNATSHRAKR1B1SLC22A6GPR84 | |
| Succinic Acid SCHEMBL28844915 | 0.87 | EGLN1 (0.64) | LMNATSHRNFKB1PMP22AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786492-B1 | Method for disposal of a plastic molded product | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 2004-12-15 | — | — | EP | disclosed |
| US-5874482-A | IMMERSING SAID THERMOSET PLASTIC MOLDED PRODUCT IN AN ALKALINE AQUEOUS SOLUTION TO PROMOTE PERMEATION AND PENETRATION OF SAID ALKALINE AQUEOUS SOLUTION INTO SAID THERMOSET PLASTIC MOLDED PRODUCT, CAUSING SOFTENING, WEAKENING | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1999-02-23 | — | — | US | disclosed |
| EP-0786492-A2 | Plastic molded product and method for disposal of the same | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |