Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8496110 | 1.00 | LMNA (0.46) | LMNAMAPTSMN1; SMN2TSHRPMP22 | |
| SCHEMBL11303799 | 0.81 | LMNA (0.50) | LMNAMAPTSMN1; SMN2TSHRPMP22 | |
| SCHEMBL8771949 | 0.80 | POLB (0.50) | LMNAPOLBGAACA1CA2 | |
| SCHEMBL11134817 | 0.80 | LMNA (0.62) | LMNAMAPTSMN1; SMN2TSHRPMP22 | |
| SCHEMBL6552632 | 0.80 | POLB (0.50) | LMNAPOLBGAACA1CA2 | |
| SCHEMBL6536580 | 0.77 | LMNA (0.51) | LMNAMAPTSMN1; SMN2TSHRPMP22 | |
| SCHEMBL1055675 | 0.76 | LMNA (0.58) | LMNAMAPTSMN1; SMN2TSHRPMP22 | |
| SCHEMBL2583193 | 0.76 | LMNA (0.58) | LMNAMAPTSMN1; SMN2TSHRPMP22 | |
| SCHEMBL2585372 | 0.74 | LMNA (0.46) | LMNAMAPTSMN1; SMN2TSHRPMP22 | |
| SCHEMBL2585374 | 0.74 | LMNA (0.46) | LMNAMAPTSMN1; SMN2TSHRPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788507-B1 | L-PYRANOSYL NUCLEOSIDES | GENENCOR INT (US) | 2004-12-15 | — | — | EP | disclosed |