Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.41 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.41 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.41 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.37 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8771949 | 1.00 | POLB (0.50) | POLBGAACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL17198380 | 0.82 | TDP1 (0.45) | TDP1SLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL6552554 | 0.80 | LMNA (0.46) | POLBGAACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8496110 | 0.80 | LMNA (0.46) | POLBGAACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29508578 | 0.78 | TDP1 (0.38) | TDP1SLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL25329700 | 0.78 | TDP1 (0.48) | TDP1SLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL24066396 | 0.76 | SLC28A1 (0.46) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL6545745 | 0.76 | SLC28A1 (0.62) | TDP1SLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL6226229 | 0.76 | SLC28A1 (0.62) | TDP1SLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL16452370 | 0.76 | SLC28A1 (0.52) | TDP1SLC28A1SLC28A2SLC29A1SLC28A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788507-B1 | L-PYRANOSYL NUCLEOSIDES | GENENCOR INT (US) | 2004-12-15 | — | — | EP | disclosed |
| US-5885972-A | ANTICARCINOGENIC AGENT | GENENCOR INTERNATIONAL, INC. (US) | 1999-03-23 | — | — | US | disclosed |
| EP-0788507-A1 | L-PYRANOSYL NUCLEOSIDES | GENENCOR INTERNATIONAL, INC. (US) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996012728-A1 | L-PYRANOSYL NUCLEOSIDES | GENENCOR INTERNATIONAL, INC. (US) | 1996-05-02 | — | — | WO | disclosed |