Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.51 |
| ▸ | HTR3B | O95264 | 1/20 | 0.51 |
| ▸ | HTR5A | P47898 | 1/20 | 0.51 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.51 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | KHK | P50053 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1255943 | 0.80 | ADRB1 (0.51) | HTR3ASIGMAR1HTR3EHTR3BHTR3D | |
| SCHEMBL6573778 | 0.77 | HTR1A (0.51) | HTR3ASIGMAR1HTR3EHTR3BHTR5A | |
| SCHEMBL877827 | 0.76 | ADRB1 (0.40) | ADRB1HTR1AHTR1D | |
| SCHEMBL4709116 | 0.75 | SUV39H2 (0.46) | ADRB1 | |
| SCHEMBL877826 | 0.73 | ADRB1 (0.35) | ADRB1 | |
| SCHEMBL27616096 | 0.72 | HTR3A (0.55) | HTR3ASIGMAR1HTR3EHTR3BHTR5A | |
| SCHEMBL30870394 | 0.69 | HTR3A (1.00) | HTR3ASIGMAR1HTR3EHTR3BHTR5A | |
| SCHEMBL3138664 | 0.69 | HTR3A (1.00) | HTR3ASIGMAR1HTR3EHTR3BHTR5A | |
| Hydrochloric Acid SCHEMBL29688470 | 0.68 | HTR3A (0.96) | HTR3ASIGMAR1HTR3EHTR3BHTR5A | |
| Hydrochloric Acid SCHEMBL15708159 | 0.68 | HTR3A (0.96) | HTR3ASIGMAR1HTR3EHTR3BHTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409476-B1 | PHARMACEUTICAL COMPOUNDS WITH SEROTONIN RECEPTOR ACTIVITY | LILLY CO ELI (US) | 2004-12-15 | — | — | EP | disclosed |