Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553232 | 0.87 | HTR2A (0.51) | HTR2AKCNH2LMNASMN1; SMN2NPC1 | |
| SCHEMBL6540742 | 0.83 | HTR2A (0.55) | HTR2AKCNH2PKMHTTPOLB | |
| SCHEMBL6540455 | 0.79 | ALDH1A1 (0.50) | HTR2AKCNH2POLBALDH1A1LMNA | |
| SCHEMBL14783546 | 0.78 | SMN1; SMN2 (0.60) | ALDH1A1LMNASMN1; SMN2NPC1MAPT | |
| SCHEMBL6554323 | 0.74 | POLB (0.52) | HTR2AKCNH2PKMPOLBLMNA | |
| SCHEMBL6554319 | 0.73 | HTR2A (0.49) | HTR2AKCNH2PKMHTTPOLB | |
| SCHEMBL6541334 | 0.71 | ALDH1A1 (0.57) | HTR2AKCNH2ALDH1A1GAA | |
| SCHEMBL24334708 | 0.70 | HTT (0.60) | HTTPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6683308 | 0.70 | CA1 (0.47) | PKMLMNASMN1; SMN2NPC1MAPT | |
| SCHEMBL27584202 | 0.68 | CA2 (0.64) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |