Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6554319 | 0.89 | HTR2A (0.49) | POLBMAPTPKMHTR2AKCNH2 | |
| SCHEMBL6540742 | 0.85 | HTR2A (0.55) | POLBPKMHTR2AKCNH2HTR6 | |
| SCHEMBL6541334 | 0.83 | ALDH1A1 (0.57) | HTR2AKCNH2HTR6 | |
| SCHEMBL12569396 | 0.77 | TAAR1 (0.57) | POLBMAPTPKMELANECYP1A2 | |
| SCHEMBL6540432 | 0.74 | KCNH2 (0.45) | POLBMAPTHTR2AKCNH2KMT2A | |
| SCHEMBL6552886 | 0.74 | HTR2A (0.48) | POLBMAPTPKMHTR2AKCNH2 | |
| SCHEMBL9343618 | 0.72 | PKM (1.00) | POLBMAPTPKMKMT2AMEN1 | |
| SCHEMBL6553077 | 0.71 | CA2 (0.46) | HTR2AKCNH2CA12CA1CA2 | |
| SCHEMBL6540455 | 0.71 | ALDH1A1 (0.50) | POLBHTR2AKCNH2KMT2ACA12 | |
| SCHEMBL6553232 | 0.69 | HTR2A (0.51) | MAPTHTR2AKCNH2CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |