SCHEMBL6553025

SCHEMBL6553025

Cc1cc(N)ccc1C=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
TSHR P16473 3/20 0.48
PDE10A Q9Y233 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
CASP1 P29466 3/20 0.44
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
PKM P14618 1/20 0.43
CYP3A4 P08684 2/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
KDM4E B2RXH2 3/20 0.41
MAPT P10636 3/20 0.41
LMNA P02545 2/20 0.41
THRB P10828 2/20 0.41
ALOX15 P16050 1/20 0.41
POLB P06746 1/20 0.41
CASP6 P55212 1/20 0.41
GAA P10253 2/20 0.40
ACHE P22303 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31018721 1.00 ALDH1A1 (0.52) ALDH1A1TSHRPDE10AL3MBTL1CASP1
Hydrochloric Acid SCHEMBL28241402 0.98 ALDH1A1 (0.50) ALDH1A1TSHRPDE10AL3MBTL1CASP1
SCHEMBL28308080 0.87 NPC1 (0.43) ALDH1A1TSHRPDE10AL3MBTL1CASP1
SCHEMBL10085458 0.82 ALDH1A1 (0.52) ALDH1A1TSHRPDE10AL3MBTL1CASP1
SCHEMBL28304117 0.81 ALDH1A1 (0.56) ALDH1A1TSHRPDE10AL3MBTL1CASP1
SCHEMBL9033276 0.81 ALDH1A1 (0.56) ALDH1A1TSHRPDE10AL3MBTL1CASP1
SCHEMBL7258077 0.79 ALDH1A1 (0.45) ALDH1A1TSHRPDE10AL3MBTL1CASP1
SCHEMBL13763239 0.79 ALDH1A1 (0.45) ALDH1A1TSHRPDE10AL3MBTL1CASP1
SCHEMBL11664879 0.78 LMNA (0.46) ALDH1A1TSHRCASP1CYP3A4MEN1
SCHEMBL27266799 0.77 ALDH1A1 (0.52) ALDH1A1TSHRPDE10AL3MBTL1CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024110327-A2 THERMOSTABLE METHINE DYES LANXESS DEUTSCHLAND GMBH (DE) 2024-05-30 WO claimed
CN-115304472-A Synthetic method of intermediate 4-bromo-2-methylbenzoic acid of Freund Lei Lana 重庆医药高等专科学校 2022-11-08 CN claimed
CN-115141097-A Intermediate 4-bromine of Freund Lei Lana-2-methylbenzoic acid's production line system 重庆医药高等专科学校 2022-10-04 CN claimed
CN-109928890-B Preparation method of tolvaptan intermediate 2-methyl-4-N- (2-methylbenzoyl) benzoic acid 重庆常捷医药有限公司 2021-11-09 CN claimed
CN-109928890-A A kind of preparation method of tolvaptan intermediate 2- methyl -4-N- (2- toluyl) benzoic acid 重庆常捷医药有限公司 2019-06-25 CN claimed
CN-106675082-B A method of preparing disperse blue 354 江苏道博化工有限公司 2019-04-05 CN claimed
CN-106242107-B A kind of vehicular handles the complete set of equipments and its processing method of ferromanganese ion in mine water 徐州市城区水资源管理处 2019-03-01 CN claimed
CN-106675082-A Method for preparing disperse blue 354 江苏道博化工有限公司 2017-05-17 CN claimed
CN-106242107-A A kind of vehicular processes complete set of equipments and the processing method thereof of ferromanganese ion in mine water 徐州市城区水资源管理处 2016-12-21 CN claimed
US-20250215467-A1 L-THREONINE TRANSALDOLASES AND USES THEREOF UNIVERSITY OF DELAWARE (US) 2025-07-03 US disclosed
WO-2024110327-A3 YELLOW METHINE DYES AND THEIR USE FOR DYEING PLASTICS LANXESS DEUTSCHLAND GMBH (DE) 2024-07-18 WO disclosed
WO-2024110327-A2 THERMOSTABLE METHINE DYES LANXESS DEUTSCHLAND GMBH (DE) 2024-05-30 WO disclosed
WO-2024110327-A2 THERMOSTABLE METHINE DYES LANXESS DEUTSCHLAND GMBH (DE) 2024-05-30 WO disclosed
CN-117088785-A Preparation method of 4-amino-2-methylbenzoic acid 江西金丰药业有限公司 2023-11-21 CN disclosed
EP-1016916-A1 Photographic element containing high dye-yield couplers EASTMAN KODAK COMPANY (US) 2000-07-05 EP disclosed
EP-1016653-A1 Preparation of high-dye yield couplers and intermediates useful therein EASTMAN KODAK COMPANY (US) 2000-07-05 EP disclosed
US-5208341-A Pressure sensitive copying; thermoreactive or electrochromic recording materials BAYER AKTIENGESELLSCHAFT (DE) 1993-05-04 US disclosed
EP-0480276-A2 Carbonylaminostyrene derivatives as recording material BAYER AG (DE) 1992-04-15 EP disclosed
US-4122070-A Fibers and anisotropic melts of polyazomethines E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-10-24 US disclosed
US-4048148-A Polyazomethine fibers and films E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-09-13 US disclosed