Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28304117 | 1.00 | ALDH1A1 (0.56) | ALDH1A1PDE10ACASP1CYP3A4TSHR | |
| SCHEMBL16900545 | 0.91 | CYP19A1 (0.49) | ALDH1A1PDE10ACASP1MEN1KMT2A | |
| SCHEMBL9294673 | 0.89 | CYP19A1 (0.52) | ALDH1A1PDE10AMEN1KMT2AMAPT | |
| SCHEMBL13763238 | 0.89 | ALDH1A1 (0.50) | ALDH1A1PDE10ACASP1CYP3A4TSHR | |
| SCHEMBL28496142 | 0.89 | ALDH1A1 (0.50) | ALDH1A1PDE10ACASP1CYP3A4TSHR | |
| SCHEMBL12810945 | 0.89 | ALDH1A1 (0.50) | ALDH1A1PDE10ACASP1CYP3A4TSHR | |
| SCHEMBL14159487 | 0.86 | ALDH1A1 (0.43) | ALDH1A1PDE10ACASP1CYP3A4TSHR | |
| SCHEMBL27856085 | 0.86 | CYP19A1 (0.55) | ALDH1A1KDM4EMAPTL3MBTL1POLB | |
| SCHEMBL23863464 | 0.83 | ALDH1A1 (0.45) | ALDH1A1PDE10ACASP1CYP3A4TSHR | |
| SCHEMBL7258077 | 0.83 | ALDH1A1 (0.45) | ALDH1A1PDE10ACASP1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7812156-B2 | Optical brightening agents | CLARIANT FINANCE (BVI) LIMITED (VG) | 2010-10-12 | — | — | US | disclosed |
| US-20070287842-A1 | Conjugated Thiophenes Having Conducting Properties and Synthesis of Same | UNIVERSITE DE MONTREAL (CA) | 2007-12-13 | — | — | US | disclosed |
| US-20070245503-A1 | Improvements Relating to Optical Brightening Agents | ARCHROMA IP GMBH (CH) | 2007-10-25 | — | — | US | disclosed |
| US-20070186358-A1 | Concentrated optical brightener solutions | CLARIANT FINANCE (BVI) LIMITED (VG) | 2007-08-16 | — | — | US | disclosed |
| EP-0708796-A1 | PROCESS FOR PREPARING COMPOSITES BASED ON ORIENTED MESOGENIC THERMOSET RESINS | THE DOW CHEMICAL COMPANY (US) | 1996-05-01 | — | — | EP | disclosed |
| EP-0573573-A1 | MESOGENIC GLYCIDYL AMINES | THE DOW CHEMICAL COMPANY (US) | 1993-12-15 | — | — | EP | disclosed |
| WO-1992015630-A2 | MESOGENIC GLYCIDYL AMINES | THE DOW CHEMICAL COMPANY (US) | 1992-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287842-A1 | Conjugated Thiophenes Having Conducting Properties and Synthesis of Same | DDT, DDC, TRPA1 | ALDH1A1 91/4885PDE10A 4541/4885CASP1 3804/4885 |
| US-20070245503-A1 | Improvements Relating to Optical Brightening Agents | TYR, MAP1LC3B, MAP1LC3A | ALDH1A1 1653/4885PDE10A 2174/4885CASP1 1965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.