Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555483 | 0.88 | ALDH1A1 (0.50) | ALDH1A1LMNAL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL15638651 | 0.85 | KIF18A (0.47) | ALDH1A1LMNAPSEN1PSEN2APH1B | |
| SCHEMBL6554749 | 0.80 | PSEN1 (0.59) | ALDH1A1LMNAPSEN1PSEN2APH1B | |
| SCHEMBL69171 | 0.79 | PSEN1 (0.61) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL29368302 | 0.79 | PSEN1 (0.61) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6555394 | 0.73 | PSEN1 (0.48) | ALDH1A1LMNAPSEN1PSEN2APH1B | |
| Toluene SCHEMBL27750047 | 0.72 | PSEN1 (0.50) | ALDH1A1LMNAPSEN1PSEN2APH1B | |
| SCHEMBL6553172 | 0.71 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1SMN1; SMN2MAPK1TDP1 | |
| SCHEMBL6554646 | 0.70 | ALDH1A1 (0.50) | ALDH1A1LMNAL3MBTL1SMN1; SMN2MAPK1 | |
| SCHEMBL6554554 | 0.70 | HSD11B1 (0.39) | ALDH1A1PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1174028-B1 | SULFONAMIDE DERIVATIVES | SUMITOMO CHEM TAKEDA AGRO CO (JP) | 2004-12-22 | — | — | EP | claimed |