Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2536552 | 0.85 | AR (0.38) | ARTRPV4HSD17B10LMNAMEN1 | |
| SCHEMBL8888822 | 0.81 | FFAR1 (0.31) | — | |
| SCHEMBL233007 | 0.79 | ALDH1A1 (0.44) | ARALDH1A1KDM4EUSP2GAA | |
| SCHEMBL127280 | 0.78 | ALDH1A1 (0.39) | HSD17B10MEN1MAPTALOX15KMT2A | |
| SCHEMBL10458094 | 0.76 | ALDH1A1 (0.38) | HSD17B10LMNAMEN1MAPTKMT2A | |
| SCHEMBL27923358 | 0.76 | MAOB (0.50) | LMNAMAPTALDH1A1MAPK1XDH | |
| SCHEMBL8126981 | 0.75 | KCNH2 (0.40) | HSD17B10MAPTALOX15ALDH1A1KDM4E | |
| SCHEMBL5451 | 0.75 | SMN1; SMN2 (0.51) | ARHSD17B10LMNAMEN1MAPT | |
| SCHEMBL30283197 | 0.75 | SMN1; SMN2 (0.51) | ARHSD17B10LMNAMEN1MAPT | |
| Hydrochloric Acid SCHEMBL27764098 | 0.73 | NPC1 (0.50) | ARHSD17B10LMNAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0851857-B1 | INHIBITORS OF TUMOR NECROSIS FACTOR ALPHA | CELGENE CORP (US) | 2004-02-18 | — | — | EP | claimed |
| EP-0957091-B1 | Inhibitors of tumor necrosis factor alpha | CELGENE CORP (US) | 2003-06-04 | — | — | EP | claimed |
| EP-2900645-B1 | HERBICIDAL AND FUNGICIDAL 3-PHENYLISOXAZOLIN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2019-08-21 | — | — | EP | disclosed |
| US-9585392-B2 | 3-phenylisoxazolin derivatives with herbicidal action | BAYER CROPSCIENCE AG (DE) | 2017-03-07 | — | — | US | disclosed |
| US-20150245615-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | BAYER CROPSCIENCE AG (DE) | 2015-09-03 | — | — | US | disclosed |
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| EP-0851857-B1 | INHIBITORS OF TUMOR NECROSIS FACTOR ALPHA | CELGENE CORP (US) | 2004-02-18 | — | — | EP | disclosed |
| EP-1367051-A2 | Inhibitors of tumor necrosis factor alpha | CELGENE CORPORATION (US) | 2003-12-03 | — | — | EP | disclosed |
| EP-0957091-B1 | Inhibitors of tumor necrosis factor alpha | CELGENE CORP (US) | 2003-06-04 | — | — | EP | disclosed |
| EP-0957091-A1 | Inhibitors of tumor necrosis factor alpha | CELGENE CORPORATION (US) | 1999-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150245615-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | CYP4X1, CBR3, PAOX | AR 4187/4885TRPV4 2766/4885HSD17B10 708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.