Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17046313 | 0.86 | ALDH1A1 (0.41) | ARXDHALDH1A1KMT2AMEN1 | |
| SCHEMBL6553336 | 0.85 | AR (0.38) | ARTRPV4XDHHSD17B10ALDH1A1 | |
| SCHEMBL21268419 | 0.84 | ALDH1A1 (0.47) | ARXDHALDH1A1HPGDCYP1A2 | |
| SCHEMBL21268212 | 0.81 | AR (0.41) | ARALDH1A1HPGD | |
| SCHEMBL27712841 | 0.81 | XDH (0.44) | XDH | |
| SCHEMBL230031 | 0.79 | ALDH1A1 (0.48) | ARALDH1A1KDM4EPOLBUSP2 | |
| SCHEMBL127280 | 0.78 | ALDH1A1 (0.39) | HSD17B10ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL21268241 | 0.77 | KDM4E (0.41) | ARHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL1231501 | 0.76 | ALDH1A1 (0.38) | HSD17B10ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL9035559 | 0.76 | MAOB (0.50) | XDHMAPTMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11970486-B2 | Compounds and uses thereof | JANSSEN PHARMACEUTICA NV (BE) | 2024-04-30 | — | — | US | disclosed |
| US-20240124435-A1 | COMPOUNDS AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2024-04-18 | — | — | US | disclosed |
| CN-117777121-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-29 | — | — | CN | disclosed |
| US-11873298-B2 | Compounds and uses thereof | JANSSEN PHARMACEUTICA NV (BE) | 2024-01-16 | — | — | US | disclosed |
| CN-110099898-B | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2023-07-25 | — | — | CN | disclosed |
| EP-3700934-A1 | COMPOUNDS AND USES THEREOF | Yumanity Therapeutics, Inc. (US) | 2020-09-02 | — | — | EP | disclosed |
| US-20200262828-A1 | COMPOUNDS AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2020-08-20 | — | — | US | disclosed |
| WO-2019209948-A9 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-01-02 | — | — | WO | disclosed |
| EP-3529245-A1 | COMPOUNDS AND USES THEREOF | Yumanity Therapeutics, Inc. (US) | 2019-08-28 | — | — | EP | disclosed |
| EP-2900645-B1 | HERBICIDAL AND FUNGICIDAL 3-PHENYLISOXAZOLIN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2019-08-21 | — | — | EP | disclosed |
| US-4354975-A | Processes for making phosphorus derivatives of aminothiomethylcarbamates | THE UPJOHN COMPANY (US) | 1982-10-19 | — | — | US | disclosed |
| US-4336207-A | Phosphorus derivatives of aminothiocarbamoyl halides | THE UPJOHN COMPANY (US) | 1982-06-22 | — | — | US | disclosed |
| US-4308217-A | Disulfides of amides of phosphoric acid | THE UPJOHN COMPANY (US) | 1981-12-29 | — | — | US | disclosed |
| US-4279840-A | Processes for making phosphorus containing aminothiocarbamoyl halides | THE UPJOHN COMPANY (US) | 1981-07-21 | — | — | US | disclosed |
| US-4279839-A | Processes for making phosphorus containing aminothiocarbamoyl halides | THE UPJOHN COMPANY (US) | 1981-07-21 | — | — | US | disclosed |
| US-4256898-A | INTERMEDIATES FOR MAKING (ALPHAS, 5S)-ALPHA-AMINO-3-CHLORO-2-ISOXAZOLINE-5-ACETIC ACID (AT-125) | THE UPJOHN COMPANY (US) | 1981-03-17 | — | — | US | disclosed |
| US-4234521-A | Phosphorus derivatives of aminothiocarbamoyl halides | THE UPJOHN COMPANY (US) | 1980-11-18 | — | — | US | disclosed |
| US-4208409-A | N-[(phosphinyl or phosphinothioyl)amino]thio-methylcarbamates and pesticidal methods | THE UPJOHN COMPANY (US) | 1980-06-17 | — | — | US | disclosed |
| US-4201733-A | PESTICIDES | THE UPJOHN COMPANY (US) | 1980-05-06 | — | — | US | disclosed |
| US-4081536-A | N-[(phosphinyl) amino]thio- and N-[(phosphinothioyl)amino]-thio-methylcarbamates and methods for controlling insects | THE UPJOHN COMPANY (US) | 1978-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240124435-A1 | COMPOUNDS AND USES THEREOF | NLN, ACHE, CLN6 | AR 4802/4885TRPV4 464/4885XDH 270/4885 |
| US-11873298-B2 | Compounds and uses thereof | NLN, ACHE, CLN6 | AR 4802/4885TRPV4 464/4885XDH 270/4885 |
| US-20200262828-A1 | COMPOUNDS AND USES THEREOF | NLN, ACHE, CLN6 | AR 4802/4885TRPV4 464/4885XDH 270/4885 |
| US-11970486-B2 | Compounds and uses thereof | NLN, ACHE, CLN6 | AR 4802/4885TRPV4 464/4885XDH 270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.