Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7215321 | 0.98 | LMNA (0.36) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL10440035 | 0.98 | LMNA (0.36) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL18276 | 0.92 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL733100 | 0.90 | SMN1; SMN2 (0.36) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL5575152 | 0.87 | LMNA (0.39) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL13318373 | 0.87 | LMNA (0.39) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL7177498 | 0.87 | LMNA (0.39) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL14713422 | 0.87 | LMNA (0.32) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL12109464 | 0.85 | SMN1; SMN2 (0.33) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL17123471 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000950-B1 | Novel indanylidene compounds | HOFFMANN LA ROCHE (CH) | 2004-02-25 | — | — | EP | disclosed |
| EP-0933376-B1 | Silanyl-triazines as light screening compositions | HOFFMANN LA ROCHE (CH) | 2003-08-20 | — | — | EP | disclosed |
| US-6416746-B1 | ULTRAVIOLET RAY AND LIGHT SCREENING MATERIAL GRAFTED TO SILANE, OLIGOSILOXANE, OR POLYSILOXANE WITH IMPROVED SOLUBILITY AND LITTLE PENETRATION; FOR USE IN COSMETICS | ROCHE VITAMINS INC. | 2002-07-09 | — | — | US | disclosed |
| EP-1000950-A2 | Novel indanylidene compounds | F. HOFFMANN-LA ROCHE AG (CH) | 2000-05-17 | — | — | EP | disclosed |
| US-6018044-A | TRIS((ALKYL, SILANE, OLIGOSILOXANE OR POLYSILOXANE)(OXY OR AMINO)CARBONYL-(1,4-PHENYLENE)-AMINO)-S-TRIAZINES HAVING AT LEAST ONE SILICON CONTAINING MOIETY OF GIVEN FORMULA; USE AS UV-B FILTERS IN LIGHT SCREENING COMPOSITIONS | ROCHE VITAMINS INC. (US) | 2000-01-25 | — | — | US | disclosed |
| EP-0933376-A2 | Silanyl-triazines as light screening compositions | F. HOFFMANN-LA ROCHE AG (CH) | 1999-08-04 | — | — | EP | disclosed |