Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.67 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 5/20 | 0.41 |
| ▸ | PPOX | P50336 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 3/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17017132 | 0.80 | PARP1 (1.00) | PARP1CDK4CCND1CES1PPOX | |
| SCHEMBL6340545 | 0.72 | PARP1 (0.79) | PARP1CDK4CCND1CES1PPOX | |
| SCHEMBL14463611 | 0.69 | PARP1 (0.59) | PARP1PPOXTDP2GSK3B | |
| SCHEMBL2951374 | 0.68 | PARP1 (0.53) | PARP1PPOXGSK3B | |
| SCHEMBL2254584 | 0.68 | PARP1 (0.53) | PARP1CDK4CCND1CES1CTRC | |
| SCHEMBL17425970 | 0.68 | CDC25B (0.56) | PARP1PPOXTDP2GSK3B | |
| SCHEMBL19116380 | 0.66 | CYP19A1 (0.49) | PARP1CES1 | |
| SCHEMBL16939655 | 0.66 | CES1 (0.62) | PARP1CES1TDP2 | |
| SCHEMBL3092491 | 0.66 | PARP1 (0.39) | PARP1CES1 | |
| SCHEMBL11880591 | 0.65 | PARP1 (0.48) | PARP1PPOXTDP2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922732-B1 | Thermoplastic elastomer triblend from an engineering thermoplastic, functionalized ethylene and or diene polymer, and brominated isobutylene P-methylstyrene copolymer | ADVANCED ELASTOMER SYSTEMS (US) | 2004-02-25 | — | — | EP | disclosed |
| US-6069202-A | IMPROVED HIGH TEMPERATURE PERFORMANCE WHILE RETAINING EXCELLENT ELONGATION CHARACTERISTICS | ADVANCED ELASTOMER SYSTEMS, L.P. (US) | 2000-05-30 | — | — | US | disclosed |
| EP-0922732-A2 | Thermoplastic elastomer triblend from an engineering thermoplastic, functionalized ethylene and or diene polymer, and brominated isobutylene P-methylstyrene copolymer | Advanced Elastomer Systems, L.P. (US) | 1999-06-16 | — | — | EP | disclosed |
| EP-0329555-A1 | Thermally stabilized blends of polyamide and polyphenylene ether | GE CHEMICALS, INC. (US) | 1989-08-23 | — | — | EP | disclosed |