Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.79 |
| ▸ | PPOX | P50336 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | PRKCH | P24723 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | MAP3K10 | Q02779 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.38 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 7/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17017132 | 0.89 | PARP1 (1.00) | PARP1PPOXGSK3BTDP2CES1 | |
| SCHEMBL11763384 | 0.79 | PARP1 (0.60) | PARP1PPOXTDP2CES1KDM4E | |
| SCHEMBL11880591 | 0.72 | PARP1 (0.48) | PARP1PPOXGSK3BTDP2KDM4E | |
| SCHEMBL6553368 | 0.72 | PARP1 (0.67) | PARP1PPOXGSK3BTDP2CES1 | |
| SCHEMBL29762371 | 0.70 | PARP1 (0.50) | PARP1PPOXTDP2KDM4EALDH1A1 | |
| SCHEMBL10607840 | 0.68 | PARP1 (0.53) | PARP1PPOXGSK3BTDP2CHEK1 | |
| SCHEMBL1756151 | 0.67 | PARP1 (0.47) | PARP1PPOXGSK3BCHEK1WEE1 | |
| SCHEMBL8592676 | 0.67 | PARP1 (0.53) | PARP1PPOXGSK3BCDK4CCND1 | |
| SCHEMBL4283299 | 0.67 | ALDH1A1 (0.47) | CES1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4608122 | 0.65 | PARP1 (0.39) | PARP1CES1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050080260-A1 | Preparation of prodrugs for selective drug delivery | LUMINIDE | 2005-04-14 | — | — | US | claimed |
| CN-109912937-A | A kind of new-energy automobile power battery insulating heat-conduction material and preparation method thereof | 杨记周 | 2019-06-21 | — | — | CN | disclosed |
| US-20050080260-A1 | Preparation of prodrugs for selective drug delivery | LUMINIDE | 2005-04-14 | — | — | US | disclosed |
| US-20050080260-A1 | Preparation of prodrugs for selective drug delivery | LUMINIDE | 2005-04-14 | — | — | US | disclosed |
| EP-0814121-B1 | Low density, fire retardant one-part epoxy composition | MINNESOTA MINING & MFG (US) | 2001-09-26 | — | — | EP | disclosed |
| EP-0814121-A1 | Low density, fire retardant one-part epoxy composition | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-12-29 | — | — | EP | disclosed |
| US-5019605-A | Hardener, smoke suppressant, filler | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0388037-A2 | Low density self-extinguishing epoxide composition | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-09-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080260-A1 | Preparation of prodrugs for selective drug delivery | APEH, PAH, ALAD | PARP1 3179/4885PPOX 22/4885DAPK3 3140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.