Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | PPOX | P50336 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10607840 | 0.81 | PARP1 (0.53) | PARP1MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL28688565 | 0.71 | PARP1 (0.45) | PARP1MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL2662415 | 0.70 | MAOA (0.43) | PARP1MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL17017132 | 0.69 | PARP1 (1.00) | PARP1PPOXGSK3B | |
| SCHEMBL2653820 | 0.69 | KDM4E (0.42) | PARP1MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL6553368 | 0.68 | PARP1 (0.67) | PARP1PPOXGSK3B | |
| SCHEMBL1756151 | 0.67 | PARP1 (0.47) | PARP1MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL27841104 | 0.66 | MAOA (0.40) | PARP1MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL6340545 | 0.65 | PARP1 (0.79) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28293878 | 0.65 | MAOA (0.39) | PARP1MAOAMAOBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759420-B2 | Layered silicate and thermoplastic resin composition containing it | TEIJIN LIMITED (JP) | 2010-07-20 | — | — | US | disclosed |
| EP-1538183-B1 | THERMOPLASTIC FILM, THERMOPLASTIC RESIN COMPOSITION, AND PHYLLOSILICATE | TEIJIN LTD (JP) | 2007-10-31 | — | — | EP | disclosed |
| US-20070106004-A1 | Layered silicate and thermoplastic resin composition containing it | TEIJIN LIMITED (JP) | 2007-05-10 | — | — | US | disclosed |
| US-7189782-B2 | Thermoplastic film, thermoplastic resin composition, and phyllosilicate | TEIJIN LIMITED (JP) | 2007-03-13 | — | — | US | disclosed |
| EP-1702887-A1 | PHYLLOSILICATE AND THERMOPLASTIC RESIN COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 2006-09-20 | — | — | EP | disclosed |
| EP-1538183-A1 | THERMOPLASTIC FILM, THERMOPLASTIC RESIN COMPOSITION, AND PHYLLOSILICATE | TEIJIN LIMITED (JP) | 2005-06-08 | — | — | EP | disclosed |
| US-20050089698-A1 | Thermoplastic film, thermoplastic resin composition, and phyllosilicate | TEIJIN LIMITED (JP) | 2005-04-28 | — | — | US | disclosed |