Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.46 |
| ▸ | FOS | P01100 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | JUN | P05412 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553382 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAMTNR1AMTNR1BALOX5 | |
| SCHEMBL6556807 | 0.90 | MTNR1A (0.51) | SMN1; SMN2LMNAMTNR1AMTNR1BALOX5 | |
| SCHEMBL7103339 | 0.89 | MEN1 (0.57) | SMN1; SMN2LMNAALOX5MEN1KMT2A | |
| SCHEMBL7103335 | 0.89 | MEN1 (0.57) | SMN1; SMN2LMNAALOX5MEN1KMT2A | |
| SCHEMBL7896834 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL7896831 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL7605247 | 0.83 | MTNR1A (0.56) | SMN1; SMN2LMNAMTNR1AMTNR1BMEN1 | |
| SCHEMBL7670246 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL7021547 | 0.83 | TRPV1 (0.43) | SMN1; SMN2LMNAALOX5MEN1KMT2A | |
| SCHEMBL7021554 | 0.83 | TRPV1 (0.43) | SMN1; SMN2LMNAALOX5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135369-B1 | ALPHA-SULFIN- AND ALPHA-SULFONAMINO ACID AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-02-25 | — | — | EP | disclosed |
| US-6538159-B2 | For use in protecting plants against infestation by phytopathogenic microorganisms | SYNGENTA PARTICIPATIONS AG (CH) | 2003-03-25 | — | — | US | disclosed |
| EP-0968179-B1 | N-SULPHONYL AND N-SULPHINYL AMINO ACID AMIDES AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-09-25 | — | — | EP | disclosed |
| US-20020099241-A1 | For use in protecting plants against infestation by phytopathogenic microorganisms | SYNGENTA PARTICIPATIONS AG (CH) | 2002-07-25 | — | — | US | disclosed |
| EP-1135369-A2 | ALPHA-SULFIN- AND ALPHA-SULFONAMINO ACID AMIDES | Syngenta Participations AG (CH) | 2001-09-26 | — | — | EP | disclosed |
| US-6277849-B1 | FOR PROTECTION OF PLANTS AGAINST PHYTOPATHOGENIC MICROORGANISM INFESTATION | SYNGENTA CROP PROTECTION, INC. | 2001-08-21 | — | — | US | disclosed |
| US-6194611-B1 | FOR CONTROLLING OR PREVENTION OF PLANT INFESTATION BY PHYTOPATHOGENIC MICROORGANISMS, SUCH AS FUNGI | NOVARTIS CROP PROTECTION, INC. | 2001-02-27 | — | — | US | disclosed |
| WO-2000032569-A2 | ALPHA-SULFIN- AND ALPHA-SULFONAMINO ACID AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-06-08 | — | — | WO | disclosed |
| EP-0858448-B1 | N-SULPHONYL AND N-SULPHINYL AMINO ACID DERIVATIVES AS MICROBICIDES | NOVARTIS AG (CH) | 2000-05-31 | — | — | EP | disclosed |
| EP-0968179-A1 | N-SULPHONYL AND N-SULPHINYL AMINO ACID AMIDES AS MICROBIOCIDES | Novartis AG (CH) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998038161-A1 | N-SULPHONYL AND N-SULPHINYL AMINO ACID AMIDES AS MICROBIOCIDES | NOVARTIS AG (CH) | 1998-09-03 | — | — | WO | disclosed |
| EP-0858448-A1 | N-SULPHONYL AND N-SULPHINYL AMINO ACID DERIVATIVES AS MICROBICIDES | Novartis AG (CH) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997014677-A1 | N-SULPHONYL AND N-SULPHINYL AMINO ACID DERIVATIVES AS MICROBICIDES | NOVARTIS AG (CH) | 1997-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099241-A1 | For use in protecting plants against infestation by phytopathogenic microorganisms | CBR1, CBR3, MSR1 | SMN1; SMN2 3433/4885LMNA 3204/4885MTNR1A 322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.