Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103335 | 1.00 | MEN1 (0.57) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6553382 | 0.89 | SMN1; SMN2 (0.50) | MEN1KMT2ALMNAALOX5SMN1; SMN2 | |
| SCHEMBL6553375 | 0.89 | SMN1; SMN2 (0.50) | MEN1KMT2ALMNAALOX5SMN1; SMN2 | |
| SCHEMBL17476717 | 0.82 | MEN1 (0.67) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7015776 | 0.82 | RAB9A (0.57) | MEN1KMT2ACYP3A4ALDH1A1ALOX15 | |
| SCHEMBL7015773 | 0.82 | RAB9A (0.57) | MEN1KMT2ACYP3A4ALDH1A1ALOX15 | |
| SCHEMBL5197621 | 0.80 | CYP1A2 (0.59) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17488471 | 0.80 | MEN1 (0.63) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4947604 | 0.79 | CYP3A4 (0.60) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17667848 | 0.79 | CYP3A4 (0.60) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030224940-A1 | Alpha-sulfin-and alpha-sulfonamino acid amide derivatives | SYNGENTA CROP PROTECTION, INC. | 2003-12-04 | — | — | US | disclosed |
| CN-1422251-A | Novel alpha-sulfin-and alpha-sulfonamino acid amide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2003-06-04 | — | — | CN | disclosed |
| EP-1272461-A1 | ALPHA-SULFIN- AND ALPHA-SULFONAMINO ACID AMIDE DERIVATIVES | Syngenta Participations AG (CH) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001079160-A1 | ALPHA-SULFIN- AND ALPHA-SULFONAMINO ACID AMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030224940-A1 | Alpha-sulfin-and alpha-sulfonamino acid amide derivatives | STS, ARSA, SULT2A1 | MEN1 2787/4885KMT2A 1753/4885CYP1A2 566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.