Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.63 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.63 |
| ▸ | MIF | P14174 | 1/20 | 0.62 |
| ▸ | CPA1 | P15085 | 2/20 | 0.58 |
| ▸ | CPB1 | P15086 | 1/20 | 0.58 |
| ▸ | CPA3 | P15088 | 1/20 | 0.58 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.50 |
| ▸ | ITGAV | P06756 | 4/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.50 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.50 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553378 | 1.00 | GABBR2 (0.63) | GABBR2GABBR1MIFCPA1CPB1 | |
| SCHEMBL28335512 | 0.98 | GABBR2 (0.61) | GABBR2GABBR1MIFCPA1CPB1 | |
| SCHEMBL27291057 | 0.98 | GABBR2 (0.61) | GABBR2GABBR1MIFCPA1CPB1 | |
| SCHEMBL6178799 | 0.89 | GABBR2 (0.56) | GABBR2GABBR1MIFCPA1CPB1 | |
| SCHEMBL6177284 | 0.89 | GABBR2 (0.56) | GABBR2GABBR1MIFCPA1CPB1 | |
| SCHEMBL6177276 | 0.89 | GABBR2 (0.56) | GABBR2GABBR1MIFCPA1CPB1 | |
| SCHEMBL10523496 | 0.88 | MIF (0.54) | GABBR2GABBR1MIFCPA1CPB1 | |
| SCHEMBL6177258 | 0.88 | GABBR2 (0.54) | GABBR2GABBR1MIFCPA1CPB1 | |
| SCHEMBL503819 | 0.85 | GABBR2 (0.76) | GABBR2GABBR1MAPTCYP1A2KMT2A | |
| SCHEMBL11542680 | 0.85 | MTNR1A (0.63) | GABBR2GABBR1MIFCPA1CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111777477-B | Method for synthesizing succinic acid derivative or 3-aryl propionic acid | 四川大学 | 2021-09-14 | — | — | CN | disclosed |
| CN-111777477-A | Method for synthesizing succinic acid derivative or 3-aryl propionic acid | 四川大学 | 2020-10-16 | — | — | CN | disclosed |
| CN-107602406-B | Preparation method and content control method in racecadotril as two kinds of impurity of external standard | 陕西汉江药业集团股份有限公司 | 2019-08-20 | — | — | CN | disclosed |
| CN-107602406-A | In racecadotril as external standard two kinds of impurity preparation method and content control method | 陕西汉江药业集团股份有限公司 | 2018-01-19 | — | — | CN | disclosed |
| CN-103889954-B | 4 cyano group 3 phenyl 4 (the pyridine 3 base) butyrates that are replaced, they preparation method and as herbicide and the purposes of plant growth regulator | 拜耳知识产权有限责任公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-100376242-C | 2-aryl-propionic acid and medicine composition containing same | DOMPAY CO LTD (IT) | 2008-03-26 | — | — | CN | disclosed |
| CN-1612729-A | 2-Aryl-propionic acids and pharmaceutical compositions containing them | DOMPAY CO LTD (IT) | 2005-05-04 | — | — | CN | disclosed |
| EP-1070043-B1 | ASYMMETRIC HYDROGENATION | CHIROTECH TECHNOLOGY LTD (GB) | 2004-02-18 | — | — | EP | disclosed |
| US-6414187-B1 | PREPARING ENANTIOMERICALLY ENRICHED CARBOXYLIC ACID DERIVATIVE BY FORMING SALT OF DEHYDRO PRECURSOR ACID WITH STOICHIOMETRIC AMOUNT OF BASE AND ASYMMETRICALLY HYDROGENATING IN PRESENCE OF COMPLEX COMPRISING RHODIUM AND CHIRAL PHOSPHINE LIGAND | CHIROTECH TECHNOLOGY, LTD. (GB) | 2002-07-02 | — | — | US | disclosed |
| EP-1070043-A1 | ASYMMETRIC HYDROGENATION | Chirotech Technology Limited (GB) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999052852-A1 | ASYMMETRIC HYDROGENATION | CHIROTECH TECHNOLOGY LIMITED (GB) | 1999-10-21 | — | — | WO | disclosed |
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |