Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10452211 | 0.98 | ERN1 (0.36) | ERN1CYP2A6LCKFYNTDP1 | |
| SCHEMBL18475662 | 0.85 | LCK (0.43) | LCKFYNTDP1ING2TSHR | |
| SCHEMBL1199354 | 0.85 | LCK (0.43) | LCKFYNTDP1ING2TSHR | |
| SCHEMBL10931312 | 0.83 | LCK (0.41) | LCKFYNTDP1ING2TSHR | |
| SCHEMBL6520071 | 0.83 | LCK (0.41) | LCKFYNTDP1ING2TSHR | |
| SCHEMBL28510700 | 0.83 | LCK (0.41) | LCKFYNTDP1ING2TSHR | |
| SCHEMBL646278 | 0.80 | LCK (0.46) | LCKFYNTDP1ING2SNCA | |
| SCHEMBL8162990 | 0.80 | LCK (0.46) | LCKFYNTDP1ING2SNCA | |
| SCHEMBL23792366 | 0.80 | CA2 (0.43) | CYP2A6CA1CA2 | |
| SCHEMBL10452210 | 0.78 | LMNA (0.42) | ERN1CYP2A6TDP1SRCLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485470-A2 | USE OF XYLENE MONOOXYGENASE FOR THE OXIDATION OF SUBSTITUTED MONOCYCLIC AROMATIC COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-12-15 | — | — | EP | claimed |
| US-20030073206-A1 | Use of xylene monooxygenase for the oxidation of substituted monocyclic aromatic compounds | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-04-17 | — | — | US | claimed |
| WO-2003014368-A2 | USE OF XYLENE MONOOXYGENASE FOR THE OXIDATION OF SUBSTITUTED MONOCYCLIC AROMATIC COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-02-20 | — | — | WO | claimed |
| EP-1485470-A2 | USE OF XYLENE MONOOXYGENASE FOR THE OXIDATION OF SUBSTITUTED MONOCYCLIC AROMATIC COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-12-15 | — | — | EP | disclosed |
| US-20030073206-A1 | Use of xylene monooxygenase for the oxidation of substituted monocyclic aromatic compounds | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-04-17 | — | — | US | disclosed |
| WO-2003014368-A2 | USE OF XYLENE MONOOXYGENASE FOR THE OXIDATION OF SUBSTITUTED MONOCYCLIC AROMATIC COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-02-20 | — | — | WO | disclosed |
| US-4276188-A | OPTICAL BRIGHTENERS FOR COTTON AND POLYAMIDES | CIBA-GEIGY CORPORATION (US) | 1981-06-30 | — | — | US | disclosed |
| US-4014644-A | OPTICAL BRIGHTENERS FOR POLYAMIDES AND CELLULOSE | CIBA-GEIGY CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |
| US-4013642-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1977-03-22 | — | — | US | disclosed |