SCHEMBL6553728

SCHEMBL6553728

CCN(CO)c1[c]cccc1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.33
MEN1 O00255 2/20 0.32
RAB9A P51151 2/20 0.32
KMT2A Q03164 2/20 0.32
NPC1 O15118 1/20 0.32
NOX1 Q9Y5S8 1/20 0.32
GAA P10253 1/20 0.31
CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL350461 0.88 TSHR (0.38) ALDH1A1CYP3A4TSHRMEN1RAB9A
SCHEMBL4722446 0.81 TSHR (0.33) ALDH1A1CYP3A4TSHRMEN1RAB9A
SCHEMBL2456294 0.78 MAPT (0.36) ALDH1A1TSHRMEN1KMT2AGAA
SCHEMBL5554891 0.78 TSHR (0.56) ALDH1A1TSHRKMT2ACNR2
SCHEMBL11794267 0.77 PYCR1 (0.36) ALDH1A1CYP3A4TSHR
SCHEMBL6555084 0.77 MAOB (0.33) ALDH1A1CYP3A4TSHR
SCHEMBL816702 0.76 TP53 (0.34)
SCHEMBL6554157 0.76
SCHEMBL1355931 0.76 MEN1 (0.35) ALDH1A1MEN1RAB9AKMT2ANPC1
SCHEMBL1355265 0.76 ALDH1A1 (0.31) ALDH1A1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1234007-B1 OLIGOMERIC METHINE DYES CLARIANT FINANCE BVI LTD (VG) 2004-02-18 EP disclosed