SCHEMBL6553741

SCHEMBL6553741

CN(C)c1ccc(N([C]=O)c2ccc(N(C)C)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.58
TSHR P16473 6/20 0.58
ALOX15 P16050 4/20 0.58
HSD17B10 Q99714 2/20 0.58
MAPK1 P28482 4/20 0.46
MAPT P10636 3/20 0.46
TP53 P04637 2/20 0.46
HPGD P15428 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
HIF1A Q16665 1/20 0.46
CYP2A6 P11509 1/20 0.46
CYP2A13 Q16696 1/20 0.46
CYP3A4 P08684 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
SLC2A1 P11166 1/20 0.41
RAB9A P51151 2/20 0.40
NPC1 O15118 1/20 0.40
CHRM5 P08912 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2140337 0.79 ALDH1A1 (0.48) ALDH1A1TSHRMAPK1MAPTHPGD
SCHEMBL65261 0.76 ALDH1A1 (1.00) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL3096120 0.74 LMNA (0.42) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL9185763 0.74 APP (0.37) MAPTAPPCA1CA2
SCHEMBL9184951 0.74 LMNA (0.42) ALDH1A1ALOX15HSD17B10MAPTHPGD
SCHEMBL3091397 0.74 CYP2A6 (0.42) ALDH1A1ALOX15MAPK1MAPTCYP2A6
SCHEMBL194965 0.74 ALDH1A1 (0.58) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL9081716 0.73 CA1 (0.50) ALDH1A1MAPK1MAPTTP53SMN1; SMN2
SCHEMBL10012639 0.73 CYP2A6 (0.41) ALDH1A1TSHRMAPK1TP53HPGD
SCHEMBL10012596 0.73 TSHR (0.42) ALDH1A1TSHRHSD17B10MAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1076079-B1 Co-milled pigments in ink jet ink EASTMAN KODAK CO (US) 2004-02-18 EP disclosed
US-6143061-A COMPRISING WATER, A HUMECTANT, AND A DELOCALIZED CATIONIC AZO DYE DERIVED FROM THE QUATEMIZATION OF A HETEROCYCLIC AZOAMINOTHIAZOLE DYE EASTMAN KODAK COMPANY (US) 2000-11-07 US disclosed