SCHEMBL194965

SCHEMBL194965

CN(C)c1ccc([C]=O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.58
TSHR P16473 6/20 0.58
ALOX15 P16050 4/20 0.58
HSD17B10 Q99714 2/20 0.58
MAPK1 P28482 4/20 0.46
MAPT P10636 3/20 0.46
TP53 P04637 2/20 0.46
HPGD P15428 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
HIF1A Q16665 1/20 0.46
CYP2A6 P11509 1/20 0.46
CYP2A13 Q16696 1/20 0.46
CYP3A4 P08684 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
APP P05067 3/20 0.42
SLC2A1 P11166 1/20 0.41
RAB9A P51151 2/20 0.40
NPC1 O15118 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL532256 0.87 MAPK1 (0.59) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL532257 0.87 MAPK1 (0.59) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL3490748 0.78 TERT (0.45) ALDH1A1TSHRALOX15HSD17B10MAPT
SCHEMBL770159 0.78 ALDH1A1 (0.65) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL10300053 0.78 ALDH1A1 (0.65) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL547220 0.78 ALDH1A1 (0.65) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL2702568 0.77 ADRA2A (0.44) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL95662 0.77 NR3C2 (0.47) ALDH1A1MAPK1MAPTHPGDSMN1; SMN2
SCHEMBL65261 0.76 ALDH1A1 (1.00) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL104811 0.76 APP (0.32) APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 788 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116841120-A Composition for preparing ultraviolet-sensitive photoetching silver paste, and preparation method and application thereof 河北光兴半导体技术有限公司 2023-10-03 CN claimed
CN-113831302-A Benzisoselenazolone derivative and preparation method and application thereof 山东大学 2021-12-24 CN claimed
US-9695141-B2 Anticancer miliusane derivatives HONG KONG BAPTIST UNIVERSITY (HK) 2017-07-04 US claimed
US-8951508-B2 Compound DSM IP ASSETS B.V. (NL) 2015-02-10 US claimed
CN-102174035-B Aromatic dihydrazide type PLK1 (Polo-like Kinase 1) inhibitor and applications thereof UNIV CHINA PHARMA 2015-01-07 CN claimed
EP-2509571-B1 NOVEL COMPOUND DSM IP ASSETS BV (NL) 2014-09-24 EP claimed
EP-2509576-B1 Polyglycerol based UV filter comprising p-dimethylamino benzoate DSM IP ASSETS BV (NL) 2014-08-27 EP claimed
CN-103145662-A N-substituted animobutyrolactone derivatives and uses thereof SHENZHEN WANHE PHARMACEUTICAL CO LTD 2013-06-12 CN claimed
US-20130034511-A1 NOVEL COMPOUND DSM IP ASSETS B.V. (NL) 2013-02-07 US claimed
US-20130004437-A1 NOVEL COMPOUND DSM IP ASSETS B.V. (NL) 2013-01-03 US claimed
EP-0293651-B1 Dicyanovinyl-substituted furan derivatives, process for their preparation, and their use SUEDZUCKER AG (DE) 1994-02-02 EP claimed
WO-1992004450-A1 HYBRID PLASMINOGEN ACTIVATORS BEECHAM GROUP PLC (GB) 1992-03-19 WO claimed
US-4916128-A Thiadiazinones MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1990-04-10 US claimed
EP-0259268-A1 Process for the preparation of optically active beta-lactams CIBA-GEIGY AG (CH) 1988-03-09 EP claimed
US-4727079-A Brain-specific dopaminergic activity involving dihydropyridine carboxamides, dihydroquinoline and isoquinoline carboxamides UNIVERSITY OF FLORIDA (US) 1988-02-23 US claimed
US-4438136-A INHIBITION OF THROMBOXANE ACTIVITY NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1984-03-20 US claimed
EP-0013608-B1 SUBSTITUTED BICYCLO (2,2,1)HEPTANES AND HEPT-2-ENES AND THEIR PHARMACEUTICAL COMPOSITIONS NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1983-06-15 EP claimed
US-4308161-A FOR UPGRADING BLACK COLOR OF BLACK LIQUID CRYSTAL DISPLAYS GENERAL ELECTRIC COMPANY (US) 1981-12-29 US claimed
US-4308164-A Novel yellow azo dyes and dichroic liquid crystal composition made therewith GENERAL ELECTRIC COMPANY (US) 1981-12-29 US claimed
US-4308163-A IMPROVING BLACK COLOR OF DICHROIC DYES GENERAL ELECTRIC COMPANY (US) 1981-12-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130034511-A1 NOVEL COMPOUND MGLL, DGKZ, DGAT2 ALDH1A1 2800/4885TSHR 3739/4885ALOX15 106/4885
US-20130004437-A1 NOVEL COMPOUND MGLL, DGKZ, DGAT2 ALDH1A1 2800/4885TSHR 3739/4885ALOX15 106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.