Sugi Predict

Sugi Predict / Compounds / SCHEMBL655375

SCHEMBL655375

SCHEMBL655375

CCC(=O)c1ccc(F)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTR7 P34969 1/20 0.64
▸ NPC1 O15118 3/20 0.61
▸ RAB9A P51151 2/20 0.61
▸ PTPN1 P18031 1/20 0.61
▸ SMN1; SMN2 Q16637 4/20 0.57
▸ MAPT P10636 2/20 0.57
▸ L3MBTL1 Q9Y468 1/20 0.57
▸ CES2 O00748 1/20 0.54
▸ CES1 P23141 1/20 0.54
▸ PLOD2 O00469 1/20 0.53
▸ CA1 P00915 2/20 0.50
▸ CA2 P00918 2/20 0.50
▸ ALDH1A1 P00352 2/20 0.50
▸ LMNA P02545 1/20 0.50
▸ KMT2A Q03164 3/20 0.49
▸ MEN1 O00255 2/20 0.49
▸ HTT P42858 2/20 0.47
▸ HPGD P15428 1/20 0.47
▸ ALOX12 P18054 1/20 0.47
▸ NPSR1 Q6W5P4 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11485192 0.94 SMN1; SMN2 (0.68) HTR7NPC1RAB9APTPN1SMN1; SMN2
Fluorobenzene SCHEMBL27628022 0.92 SMN1; SMN2 (0.66) HTR7NPC1RAB9APTPN1SMN1; SMN2
SCHEMBL9607348 0.90 HTR7 (0.55) HTR7NPC1RAB9APTPN1SMN1; SMN2
SCHEMBL4680969 0.88 HTR7 (0.53) HTR7NPC1RAB9APTPN1SMN1; SMN2
SCHEMBL8051337 0.87 SMN1; SMN2 (0.70) HTR7NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL4926263 0.85 MEN1 (0.65) HTR7NPC1RAB9APTPN1SMN1; SMN2
SCHEMBL11612967 0.85 HTR7 (0.59) HTR7NPC1RAB9APTPN1SMN1; SMN2
Chlorobenzene SCHEMBL27609008 0.85 MAPT (0.58) HTR7NPC1RAB9APTPN1SMN1; SMN2
SCHEMBL6604902 0.83 HTR7 (0.56) HTR7NPC1RAB9APTPN1SMN1; SMN2
Ethyne SCHEMBL8050785 0.82 SMN1; SMN2 (0.64) HTR7NPC1RAB9ASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 724 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250033082-A1 METHOD AND COMPOSITION FOR REDUCING SOLVENT RELEASE FROM, AND REDUCING ODOR OF, AGROCHEMICAL FORMULATIONS ADAMA MAKHTESHIM LTD. (IL) 2025-01-30 — — US claimed
EP-4423178-A1 METHOD AND COMPOSITION FOR REDUCING SOLVENT RELEASE FROM, AND REDUCING ODOR OF, AGROCHEMICAL FORMULATIONS ADAMA MAKHTESHIM LTD. (IL) 2024-09-04 — — EP claimed
WO-2023073536-A1 METHOD AND COMPOSITION FOR REDUCING SOLVENT RELEASE FROM, AND REDUCING ODOR OF, AGROCHEMICAL FORMULATIONS ADAMA MAKHTESHIM LTD. (IL) 2023-05-04 — — WO claimed
CN-106008400-A New chalcone derivative, preparation method and application thereof in autoimmune diseases 云南省中医医院 2016-10-12 — — CN claimed
CN-105541742-A Preparation method of ezetimibe intermediate JIANGSU HANSYN PHARMACEUTICAL CO LTD 2016-05-04 — — CN claimed
CN-105017012-A Acetoxylation method of benzyl groups UNIV JIANGXI NORMAL 2015-11-04 — — CN claimed
CN-102976954-B Preparation method of chiral 2-fluoromethyl phenyl ethylamine SHANGHAI WUXI APPTEC CO LTD 2015-04-01 — — CN claimed
CN-102976953-A Preparation method of chiral alpha-difluoromethyl phenyl ethylamine WUXI APPTEC CO LTD 2013-03-20 — — CN claimed
EP-1556361-A2 2-ALKYL-(2-AMINO-3-ARYL-PROPIONYL)-PIPERAZINE DERIVATIVES AND RELATED COMPOUNDS AS MELANOCORTIN RECEPTOR LIGANDS FOR THE TREATMENT OF OBESITY THE PROCTER & GAMBLE COMPANY (US) 2005-07-27 — — EP claimed
CN-1174970-C Method of preparing 3-haloalkyl-1H-pyrazoles G��D��ɪ����˾ 2004-11-10 — — CN claimed
WO-2004037797-A2 2 - ALKYL - (2 - AMINO - 3 - ARYL - PROPIONYL) - PIPERAZINE DERIVATIVES AND RELATED COMPOUNDS AS MELANOCORTIN RECEPTOR LIGANDS FOR THE TREATMENT OF OBESITY THE PROCTER & GAMBLE COMPANY (US) 2004-05-06 — — WO claimed
CN-1190960-A Method of preparing 3-haloalkyl-1H-pyrazoles SEARLE & CO (US) 1998-08-19 — — CN claimed
US-20260124204-A1 METALLOENZYME INHIBITOR COMPOUNDS EIKONIZO THERAPEUTICS, INC. (US) 2026-05-07 — — US disclosed
US-12466781-B2 Thyromimetics AUTOBAHN THERAPEUTICS, INC. (US) 2025-11-11 — — US disclosed
US-20250333406-A1 SULFONYL CYCLIC DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF LYSOWAY THERAPEUTICS INC (US) 2025-10-30 — — US disclosed
US-12370194-B2 Metalloenzyme inhibitor compounds EIKONIZO THERAPEUTICS, INC. (US) 2025-07-29 — — US disclosed
US-4025502-A POLYMERIZATION CATALYSTS, CURING AGENTS PENNWALT CORPORATION (US) 1977-05-24 — — US disclosed
US-4009157-A POLYESTER FOAMING AGENTS, FREE RADICAL CATALYSTS PENNWALT CORPORATION (US) 1977-02-22 — — US disclosed
US-3970693-A Process for preparing indene acetic acids MERCK & CO., INC. (US) 1976-07-20 — — US disclosed
US-3944600-A Indenylidene-3-acetic acid process for preparing indene acetic acids MERCK & CO., INC. (US) 1976-03-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12466781-B2 Thyromimetics TPO, TSHR, CHRM1 HTR7 1069/4885NPC1 2320/4885RAB9A 2269/4885
US-20260124204-A1 METALLOENZYME INHIBITOR COMPOUNDS HDAC6, HDAC3, HDAC1 HTR7 2822/4885NPC1 710/4885RAB9A 340/4885
US-20250333406-A1 SULFONYL CYCLIC DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF STOML2, ATP2A3, ATP2A1 HTR7 4488/4885NPC1 362/4885RAB9A 451/4885
US-12370194-B2 Metalloenzyme inhibitor compounds HDAC6, HDAC1, HDAC2 HTR7 4058/4885NPC1 320/4885RAB9A 1505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.