Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555465 | 1.00 | MTNR1A (0.44) | MTNR1AITGB3ITGA2BALOX5MALT1 | |
| SCHEMBL6554181 | 1.00 | MTNR1A (0.44) | MTNR1AITGB3ITGA2BALOX5MALT1 | |
| Hydrochloric Acid SCHEMBL6555480 | 0.99 | MTNR1A (0.43) | MTNR1AITGB3ITGA2BALOX5MALT1 | |
| SCHEMBL7312154 | 0.90 | LTB4R (0.40) | MTNR1AITGB3ITGA2BMALT1MAPT | |
| SCHEMBL6554163 | 0.88 | MTNR1A (0.51) | MTNR1AITGB3ITGA2BALOX5MALT1 | |
| SCHEMBL6554279 | 0.88 | MTNR1A (0.51) | MTNR1AITGB3ITGA2BALOX5MALT1 | |
| SCHEMBL6553933 | 0.88 | MTNR1A (0.51) | MTNR1AITGB3ITGA2BALOX5MALT1 | |
| SCHEMBL7302536 | 0.86 | MTNR1A (0.45) | MTNR1AITGB3ITGA2BALOX5MALT1 | |
| Hydrochloric Acid SCHEMBL6555750 | 0.86 | MTNR1A (0.50) | MTNR1AITGB3ITGA2BALOX5MALT1 | |
| SCHEMBL7297144 | 0.84 | MTNR1A (0.63) | MTNR1AALOX5TP53MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892044-B1 | Esterase and its use for the production of optically active chroman compounds | MITSUI CHEMICALS INC (JP) | 2004-12-29 | — | — | EP | disclosed |
| US-6303349-B1 | CONTACTING CHROMAN-3-ACETIC ACID ESTER WITH ESTER HYDROLASE TO HYDROLYZE TO CHROMAN-3-ACETIC ACID | MITSUI CHEMICALS, INC. (JP) | 2001-10-16 | — | — | US | disclosed |
| EP-0760364-B1 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI CHEMICALS INC (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-6060290-A | DERIVED FROM BACTERIA OF GENUS PSEUDONOCARDIA | MITSUI CHEMICALS INCORPORATED (JP) | 2000-05-09 | — | — | US | disclosed |
| EP-0892044-A2 | Esterase and its use for the production of optically active chroman compounds | Mitsui Chemicals, Inc. (JP) | 1999-01-20 | — | — | EP | disclosed |
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5719145-A | FIBRINOGEN ANTAGONIST FOR TREATMENT OF THROMBOSIS, RESTENOSIS AFTER ANGIOPLASTY OR CORONARY RECANALIZATION; WATER SOLUBILITY, ORAL ADMINISTRATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0760364-A2 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |