Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555465 | 0.86 | MTNR1A (0.44) | MTNR1AMIFMALT1ITGB3ITGA2B | |
| SCHEMBL6553963 | 0.86 | MTNR1A (0.44) | MTNR1AMIFMALT1ITGB3ITGA2B | |
| SCHEMBL6554181 | 0.86 | MTNR1A (0.44) | MTNR1AMIFMALT1ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL6555480 | 0.85 | MTNR1A (0.43) | MTNR1AMIFMALT1ITGB3ITGA2B | |
| SCHEMBL7297144 | 0.85 | MTNR1A (0.63) | MTNR1AALOX5TP53MAPTLMNA | |
| SCHEMBL1519580 | 0.80 | TP53 (0.46) | DRD3TP53MAPTKMT2ALMNA | |
| SCHEMBL7312154 | 0.79 | LTB4R (0.40) | MTNR1AMIFMALT1ITGB3ITGA2B | |
| SCHEMBL7302032 | 0.78 | MAOB (0.46) | MTNR1ATP53RAB9A | |
| SCHEMBL7077031 | 0.77 | CYP19A1 (0.49) | DRD3MIFITGB3ITGA2BHSD17B1 | |
| SCHEMBL7073132 | 0.77 | CYP19A1 (0.49) | DRD3MIFHSD17B1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |