Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 20/20 | 0.60 |
| ▸ | GABRD | O14764 | 20/20 | 0.60 |
| ▸ | GABRA1 | P14867 | 20/20 | 0.60 |
| ▸ | GABRB1 | P18505 | 20/20 | 0.60 |
| ▸ | GABRG2 | P18507 | 20/20 | 0.60 |
| ▸ | GABRB3 | P28472 | 20/20 | 0.60 |
| ▸ | GABRA5 | P31644 | 20/20 | 0.60 |
| ▸ | GABRA3 | P34903 | 20/20 | 0.60 |
| ▸ | GABRA2 | P47869 | 20/20 | 0.60 |
| ▸ | GABRB2 | P47870 | 20/20 | 0.60 |
| ▸ | GABRA4 | P48169 | 20/20 | 0.60 |
| ▸ | GABRE | P78334 | 20/20 | 0.60 |
| ▸ | GABRA6 | Q16445 | 20/20 | 0.60 |
| ▸ | GABRG1 | Q8N1C3 | 20/20 | 0.60 |
| ▸ | GABRG3 | Q99928 | 20/20 | 0.60 |
| ▸ | GABRQ | Q9UN88 | 20/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6554265 | 0.88 | GABRP (0.63) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7713384 | 0.87 | GABRA2 (0.70) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7805692 | 0.86 | GABRB3 (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7811497 | 0.86 | GABRP (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7811770 | 0.86 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6553832 | 0.86 | GABRP (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7947688 | 0.85 | GABRP (0.60) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7815232 | 0.85 | GABRP (0.55) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6553857 | 0.83 | GABRA2 (0.65) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7813129 | 0.83 | GABRP (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918756-B1 | PARASITICIDAL PYRAZOLES | PFIZER LTD (GB) | 2004-02-25 | — | — | EP | disclosed |
| EP-0933363-B1 | Parasiticidal pyrazoles | PFIZER LTD (GB) | 2003-08-27 | — | — | EP | disclosed |
| EP-0946515-B1 | PARASITICIDAL PYRAZOLES | PFIZER LTD (GB) | 2003-03-05 | — | — | EP | disclosed |
| US-20020173662-A1 | Parasiticidal pyrazoles | BANKS BERNARD JOSEPH (GB) | 2002-11-21 | — | — | US | disclosed |
| EP-0846686-B1 | 1-Phenyl-pyrazol derivatives and their use as parasiticidal agents | PFIZER LTD (GB) | 2002-01-09 | — | — | EP | disclosed |
| EP-0871617-B1 | PARASITICIDAL COMPOUNDS | PFIZER (US) | 2001-11-14 | — | — | EP | disclosed |
| US-6268509-B1 | PESTICIDES | PFIZER INC | 2001-07-31 | — | — | US | disclosed |
| US-6255333-B1 | HUMANS OR ANIMALS | PFIZER INC. | 2001-07-03 | — | — | US | disclosed |
| US-6156782-A | Parasiticidal compounds | PFIZER INC (US) | 2000-12-05 | — | — | US | disclosed |
| US-6090394-A | FOR HUMANS, ANIMALS | PFIZER INC. (US) | 2000-07-18 | — | — | US | disclosed |
| US-6075043-A | Parasiticidal pyrazoles | PFIZER INC. (US) | 2000-06-13 | — | — | US | disclosed |
| US-6069157-A | Parasiticidal compounds | PFIZER INC. (US) | 2000-05-30 | — | — | US | disclosed |
| US-6028096-A | Parasiticidal pyrazoles | PFIZER INC (US) | 2000-02-22 | — | — | US | disclosed |
| EP-0933363-A1 | Parasiticidal pyrazoles | Pfizer Limited (GB) | 1999-08-04 | — | — | EP | disclosed |
| EP-0918756-A1 | PARASITICIDAL PYRAZOLES | Pfizer Limited (GB) | 1999-06-02 | — | — | EP | disclosed |
| EP-0871617-A1 | PARASITICIDAL COMPOUNDS | PFIZER INC. (US) | 1998-10-21 | — | — | EP | disclosed |
| EP-0846686-A1 | 1-Phenyl-pyrazol derivatives and their use as parasiticidal agents | Pfizer Limited (GB) | 1998-06-10 | — | — | EP | disclosed |
| WO-1998004530-A1 | PARASITICIDAL PYRAZOLES | PFIZER LIMITED (GB) | 1998-02-05 | — | — | WO | disclosed |
| WO-1997007102-A1 | PARASITICIDAL COMPOUNDS | PFIZER INC (US) | 1997-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173662-A1 | Parasiticidal pyrazoles | HRH3, HRH2, HRH1 | GABRP 799/4885GABRD 1289/4885GABRA1 399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.