Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6554019 | 0.89 | HTR6 (0.48) | HTR6CYP1A2F2TMPRSS4TSHR | |
| SCHEMBL6552312 | 0.86 | HTR6 (0.48) | HTR6CYP4F2CYP4A11CYP1A2F2 | |
| SCHEMBL6678613 | 0.86 | HTR6 (0.50) | HTR6CYP4F2CYP4A11CYP1A2F2 | |
| SCHEMBL6553968 | 0.84 | CYP4F2 (0.42) | CYP4F2CYP4A11CYP1A2POLBMAPT | |
| SCHEMBL6541353 | 0.81 | HTR6 (0.51) | HTR6CYP1A2F2TMPRSS4TSHR | |
| SCHEMBL6552306 | 0.78 | HTR6 (0.47) | HTR6CYP1A2F2TMPRSS4TSHR | |
| SCHEMBL6552876 | 0.76 | ESR1 (0.39) | CYP4F2CYP4A11POLBMAPTPKM | |
| SCHEMBL6540545 | 0.75 | HTR6 (0.47) | HTR6CYP1A2F2TMPRSS4TSHR | |
| SCHEMBL6553965 | 0.75 | NAMPT (0.37) | KMT2ANAMPTMEN1 | |
| SCHEMBL10483834 | 0.74 | KDM4E (0.56) | CYP4F2CYP4A11CYP1A2TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |