Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 7/20 | 0.38 |
| ▸ | NAMPT | P43490 | 6/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6552874 | 0.90 | ESR1 (0.38) | ESR1KCNH2CNR1ACACBNAMPT | |
| SCHEMBL6553983 | 0.90 | KMT2A (0.43) | ESR1KCNH2CNR1ACACBKMT2A | |
| SCHEMBL6540840 | 0.90 | NAMPT (0.45) | CNR1ACACBNAMPTKMT2A | |
| SCHEMBL6541730 | 0.87 | CNR1 (0.38) | ESR1KCNH2CNR1ACACBNAMPT | |
| SCHEMBL6541794 | 0.86 | PTPN1 (0.44) | CNR1ACACBNAMPT | |
| SCHEMBL6554558 | 0.85 | POLB (0.54) | ESR1KCNH2CNR1ACACBKMT2A | |
| SCHEMBL6540415 | 0.84 | CNR1 (0.40) | ESR1KCNH2CNR1ACACBMAPT | |
| SCHEMBL6552531 | 0.84 | ESR1 (0.46) | ESR1KCNH2CNR1ACACBNAMPT | |
| SCHEMBL6553980 | 0.82 | ESR1 (0.40) | ESR1KCNH2CNR1ACACBKMT2A | |
| SCHEMBL6553968 | 0.82 | CYP4F2 (0.42) | NAMPTCYP4F2CYP4A11KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |