SCHEMBL6678613

SCHEMBL6678613

CC(=O)Oc1cc(S(=O)(=O)c2ccc(CCN)cc2)ccc1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 2/20 0.50
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
CA5A P35218 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
TAAR1 Q96RJ0 3/20 0.46
TSHR P16473 3/20 0.46
MAPK1 P28482 3/20 0.46
MAPT P10636 4/20 0.45
POLB P06746 1/20 0.45
PKM P14618 1/20 0.45
LMNA P02545 3/20 0.44
GLA P06280 1/20 0.44
BACE1 P56817 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6554024 0.86 HTR6 (0.49) HTR6CA12CA1CA2CA4
SCHEMBL6552312 0.85 HTR6 (0.48) HTR6CA12CA1CA2CA4
SCHEMBL6677345 0.81 CA1 (0.53) CA12CA1CA2CA4CA9
SCHEMBL6677713 0.81 CA1 (0.43) CA12CA1CA2CA7CA9
Hydrochloric Acid SCHEMBL6681267 0.77 HTR6 (0.48) HTR6CA12CA1CA2CA4
SCHEMBL6554019 0.77 HTR6 (0.48) HTR6CA12CA1CA2CA4
SCHEMBL6541417 0.76 HTR6 (0.57) HTR6CA12CA1CA2CA4
SCHEMBL6552306 0.76 HTR6 (0.47) HTR6CA12CA1CA2CA4
SCHEMBL22558035 0.75 ALDH1A1 (0.49) CA12CA1CA2CA7CA9
SCHEMBL27634529 0.75 CYP4F2 (0.49) TAAR1TSHRMAPK1LMNAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004045610-A1 AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS FUJISAWA PHARMACEUTICAL CO., LTD (JP) 2004-06-03 WO disclosed