Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23172791 | 0.97 | LMNA (0.52) | LMNAOPRM1ALDH1A1TDP1DNM1 | |
| SCHEMBL29640413 | 0.95 | LMNA (0.54) | LMNAOPRM1DNM1TSHRCA1 | |
| SCHEMBL20821296 | 0.95 | LMNA (0.54) | LMNAOPRM1DNM1TSHRCA1 | |
| SCHEMBL5683598 | 0.95 | LMNA (0.54) | LMNAOPRM1DNM1TSHRCA1 | |
| SCHEMBL671342 | 0.95 | ALDH1A1 (0.46) | LMNAOPRM1ALDH1A1TDP1DNM1 | |
| SCHEMBL17135388 | 0.92 | LMNA (0.50) | LMNAOPRM1ALDH1A1TDP1DNM1 | |
| SCHEMBL3341567 | 0.90 | ALDH1A1 (0.42) | LMNAOPRM1ALDH1A1TDP1DNM1 | |
| SCHEMBL22471932 | 0.90 | LMNA (0.54) | LMNAOPRM1DNM1TSHRCA1 | |
| SCHEMBL4654050 | 0.89 | ALDH1A1 (0.46) | LMNAOPRM1ALDH1A1TDP1DNM1 | |
| SCHEMBL10687657 | 0.87 | OPRM1 (0.50) | LMNAOPRM1ALDH1A1TDP1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1488776-A1 | PHENYLACETONITRILE DERIVATIVES AND HAIR TONICS AND EXTERNAL PREPARATIONS FOR SKIN CONTAINING THE DERIVATIVES | Shiseido Co., Ltd. (JP) | 2004-12-22 | — | — | EP | disclosed |