Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 6/20 | 0.50 |
| ▸ | HRH1 | P35367 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.50 |
| ▸ | DRD2 | P14416 | 4/20 | 0.50 |
| ▸ | HTR2A | P28223 | 4/20 | 0.50 |
| ▸ | HTR2B | P41595 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1138175 | 0.95 | DRD3 (0.59) | SLC6A9DRD3HRH1LMNACYP2D6 | |
| SCHEMBL3139347 | 0.95 | DRD3 (0.59) | SLC6A9DRD3HRH1LMNACYP2D6 | |
| SCHEMBL1137906 | 0.85 | SLC6A9 (0.57) | SLC6A9DRD3HRH1LMNACYP2D6 | |
| SCHEMBL6554386 | 0.85 | LMNA (0.65) | DRD3HRH1LMNACYP2D6KCNH2 | |
| SCHEMBL1137901 | 0.85 | SLC6A9 (0.57) | SLC6A9DRD3HRH1LMNACYP2D6 | |
| SCHEMBL1138520 | 0.81 | KCNH2 (0.59) | SLC6A9DRD3HRH1LMNACYP2D6 | |
| SCHEMBL1137918 | 0.81 | KCNH2 (0.59) | SLC6A9DRD3HRH1LMNACYP2D6 | |
| SCHEMBL3155703 | 0.81 | LMNA (0.70) | DRD3HRH1LMNACYP2D6KCNH2 | |
| SCHEMBL1137922 | 0.81 | KCNH2 (0.59) | SLC6A9DRD3HRH1LMNACYP2D6 | |
| SCHEMBL1138522 | 0.81 | KCNH2 (0.59) | SLC6A9DRD3HRH1LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487810-A2 | 4-(DIARYLMETHYL)-1-PIPERAZINYL DERIVATIVES | Sun Pharmaceuticals Industries Ltd. (IN) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003079970-A2 | 4-(DIARYLMETHYL)-1-PIPERAZINYL DERIVATIVES | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2003-10-02 | — | — | WO | disclosed |