Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | TK2 | O00142 | 11/20 | 0.46 |
| ▸ | TK1 | P04183 | 1/20 | 0.43 |
| ▸ | DUT | P33316 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600632 | 0.92 | KIF11 (0.59) | KIF11HRH4TK2TK1DUT | |
| SCHEMBL29194837 | 0.87 | KIF11 (0.46) | KIF11HRH4TK2TK1SLC6A1 | |
| SCHEMBL29194795 | 0.87 | KIF11 (0.46) | KIF11HRH4TK2TK1SLC6A1 | |
| SCHEMBL28353747 | 0.87 | KIF11 (0.46) | KIF11HRH4TK2TK1SLC6A1 | |
| SCHEMBL27989498 | 0.84 | KIF11 (0.63) | KIF11HRH4TK2TK1DUT | |
| SCHEMBL25077435 | 0.81 | KIF11 (0.55) | KIF11HRH4TK2TK1TSHR | |
| SCHEMBL5820308 | 0.81 | KIF11 (0.55) | KIF11HRH4TK2TK1TSHR | |
| SCHEMBL9637348 | 0.81 | KIF11 (0.55) | KIF11HRH4TK2TK1DUT | |
| SCHEMBL20032419 | 0.81 | KIF11 (0.55) | KIF11HRH4TK2TK1DUT | |
| SCHEMBL21411547 | 0.81 | KIF11 (0.55) | KIF11HRH4TK2TK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0898575-B1 | A COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES | KOESTER HUBERT DR (US) | 2004-12-29 | — | — | EP | claimed |
| CN-109906230-A | Endosomolytic agent for gene therapy | UCB生物制药私人有限公司 | 2019-06-18 | — | — | CN | disclosed |