Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9780700 | 1.00 | PPARG (0.41) | PPARGPPARALTA4HALDH1A1RECQL | |
| SCHEMBL27525280 | 0.85 | LTA4H (0.40) | PPARGPPARALTA4HALDH1A1CNR1 | |
| SCHEMBL1454710 | 0.85 | LTA4H (0.44) | PPARGPPARALTA4HALDH1A1CNR1 | |
| SCHEMBL4814730 | 0.79 | MEN1 (0.47) | ALDH1A1CNR2LMNASMN1; SMN2HTT | |
| SCHEMBL7923428 | 0.76 | ALDH1A1 (0.44) | PPARGPPARALTA4HALDH1A1RECQL | |
| SCHEMBL10605190 | 0.76 | PPARG (0.40) | PPARGPPARARECQLCNR1CNR2 | |
| SCHEMBL7929047 | 0.76 | ALDH1A1 (0.44) | PPARGPPARALTA4HALDH1A1RECQL | |
| SCHEMBL28552515 | 0.75 | PPARG (0.43) | PPARGPPARALTA4HCNR1MLNR | |
| SCHEMBL382122 | 0.75 | PPARG (0.43) | PPARGPPARALTA4HCNR1MLNR | |
| SCHEMBL21991 | 0.75 | PPARG (0.43) | PPARGPPARALTA4HCNR1MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0884375-B1 | Reaction products of substituted carboxylic acylating agents and carboxylic reactants for use in fuels and lubricants | LUBRIZOL CORP (US) | 2004-12-29 | — | — | EP | disclosed |
| US-6818601-B1 | REACTION PRODUCT OF HYDROCARBON POLYMER GRAFTED WITH ALPHA,BETA-ETHYLENICALLY UNSATURATED CARBOXYLIC ACID AND AN AMINE | THE LUBRIZOL CORPORATION | 2004-11-16 | — | — | US | disclosed |
| EP-0899276-B1 | Low chlorine content compositions for use in lubricants and fuels | LUBRIZOL CORP (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6165235-A | Low chlorine content compositions for use in lubricants and fuels | THE LUBRIZOL CORPORATION (US) | 2000-12-26 | — | — | US | disclosed |
| US-5912213-A | REACTION OF OLEFIN WITH CARBOXYLIC REACTANT FOR ACYLATION | THE LUBRIZOL CORPORATION (US) | 1999-06-15 | — | — | US | disclosed |
| EP-0899276-A1 | Low chlorine content compositions for use in lubricants and fuels | The Lubrizol Corporation (US) | 1999-03-03 | — | — | EP | disclosed |
| US-5851966-A | Reaction products of substituted carboxylic acylating agents and carboxylic reactants for use in fuels and lubricants | THE LUBRIZOL CORPORATION (US) | 1998-12-22 | — | — | US | disclosed |
| EP-0884375-A1 | Reaction products of substituted carboxylic acylating agents and carboxylic reactants for use in fuels and lubricants | The Lubrizol Corporation (US) | 1998-12-16 | — | — | EP | disclosed |
| EP-0882783-A2 | Substituted carboxylic acylating agent compositions and derivatives thereof for use in lubricants and fuels | The Lubrizol Corporation (US) | 1998-12-09 | — | — | EP | disclosed |
| EP-0882782-A2 | Nitrogen-containing dispersant-viscosity improvers for lubricating oils | The Lubrizol Corporation (US) | 1998-12-09 | — | — | EP | disclosed |