SCHEMBL6554535

SCHEMBL6554535

CCCCCCCCC(COCCOCCO)Oc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
HTT P42858 2/20 0.46
THRB P10828 1/20 0.46
MAPT P10636 1/20 0.46
ALDH1A1 P00352 3/20 0.46
LMNA P02545 2/20 0.46
CYP3A4 P08684 2/20 0.46
MAPK1 P28482 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
USP2 O75604 1/20 0.46
CASP1 P29466 1/20 0.46
SLCO1B3 Q9NPD5 1/20 0.46
SLCO1B1 Q9Y6L6 1/20 0.46
TSHR P16473 1/20 0.39
LTA4H P09960 2/20 0.38
MLNR O43193 1/20 0.37
NR1I2 O75469 1/20 0.37
ESR1 P03372 1/20 0.37
NR3C1 P04150 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6554482 0.97 ALDH1A1 (0.42) MEN1KMT2AHTTTHRBMAPT
SCHEMBL330344 0.97 ALDH1A1 (0.42) MEN1KMT2AHTTTHRBMAPT
SCHEMBL28851363 0.89 LTA4H (0.40) HTTALDH1A1LMNACYP3A4MAPK1
Ammonia Solution, Strong SCHEMBL28082695 0.88 LTA4H (0.39) HTTALDH1A1LMNACYP3A4MAPK1
SCHEMBL11026453 0.88 ALDH1A1 (0.38) MEN1KMT2AALDH1A1LMNACYP3A4
SCHEMBL5704277 0.84 CSNK1E (0.42) HTTALDH1A1LMNACYP3A4MAPK1
SCHEMBL11874218 0.84 CSNK1E (0.42) HTTALDH1A1LMNACYP3A4MAPK1
SCHEMBL11497854 0.84 ALDH1A1 (0.40) MEN1KMT2AHTTTHRBMAPT
SCHEMBL11265683 0.84 LTA4H (0.38) HTTALDH1A1LMNACYP3A4MAPK1
Water SCHEMBL11423558 0.83 LTA4H (0.44) ALDH1A1LMNATSHRLTA4HRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0884375-B1 Reaction products of substituted carboxylic acylating agents and carboxylic reactants for use in fuels and lubricants LUBRIZOL CORP (US) 2004-12-29 EP disclosed
US-6818601-B1 REACTION PRODUCT OF HYDROCARBON POLYMER GRAFTED WITH ALPHA,BETA-ETHYLENICALLY UNSATURATED CARBOXYLIC ACID AND AN AMINE THE LUBRIZOL CORPORATION 2004-11-16 US disclosed
EP-0899276-B1 Low chlorine content compositions for use in lubricants and fuels LUBRIZOL CORP (US) 2003-10-29 EP disclosed
US-6165235-A Low chlorine content compositions for use in lubricants and fuels THE LUBRIZOL CORPORATION (US) 2000-12-26 US disclosed
US-5912213-A REACTION OF OLEFIN WITH CARBOXYLIC REACTANT FOR ACYLATION THE LUBRIZOL CORPORATION (US) 1999-06-15 US disclosed
EP-0899276-A1 Low chlorine content compositions for use in lubricants and fuels The Lubrizol Corporation (US) 1999-03-03 EP disclosed
US-5851966-A Reaction products of substituted carboxylic acylating agents and carboxylic reactants for use in fuels and lubricants THE LUBRIZOL CORPORATION (US) 1998-12-22 US disclosed
EP-0884375-A1 Reaction products of substituted carboxylic acylating agents and carboxylic reactants for use in fuels and lubricants The Lubrizol Corporation (US) 1998-12-16 EP disclosed
EP-0882783-A2 Substituted carboxylic acylating agent compositions and derivatives thereof for use in lubricants and fuels The Lubrizol Corporation (US) 1998-12-09 EP disclosed
EP-0882782-A2 Nitrogen-containing dispersant-viscosity improvers for lubricating oils The Lubrizol Corporation (US) 1998-12-09 EP disclosed