SCHEMBL6554482

SCHEMBL6554482

CCCCCCCCCC(COCCO)Oc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
LMNA P02545 2/20 0.42
CYP3A4 P08684 2/20 0.42
MAPK1 P28482 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
USP2 O75604 2/20 0.42
CASP1 P29466 1/20 0.42
SLCO1B3 Q9NPD5 1/20 0.42
SLCO1B1 Q9Y6L6 1/20 0.42
HTT P42858 2/20 0.41
THRB P10828 1/20 0.41
MAPT P10636 1/20 0.41
LTA4H P09960 2/20 0.40
RECQL P46063 1/20 0.39
MLNR O43193 1/20 0.38
NR1I2 O75469 1/20 0.38
ESR1 P03372 1/20 0.38
NR3C1 P04150 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL330344 1.00 ALDH1A1 (0.42) ALDH1A1MEN1KMT2ALMNACYP3A4
SCHEMBL6554535 0.97 MEN1 (0.46) ALDH1A1MEN1KMT2ALMNACYP3A4
SCHEMBL11026453 0.90 ALDH1A1 (0.38) ALDH1A1MEN1KMT2ALMNACYP3A4
SCHEMBL11874218 0.86 CSNK1E (0.42) ALDH1A1LMNACYP3A4MAPK1SMN1; SMN2
SCHEMBL5704277 0.86 CSNK1E (0.42) ALDH1A1LMNACYP3A4MAPK1SMN1; SMN2
SCHEMBL11497854 0.86 ALDH1A1 (0.40) ALDH1A1MEN1KMT2ALMNACYP3A4
SCHEMBL28851363 0.86 LTA4H (0.40) ALDH1A1LMNACYP3A4MAPK1SMN1; SMN2
Ammonia Solution, Strong SCHEMBL28082695 0.84 LTA4H (0.39) ALDH1A1LMNACYP3A4MAPK1SMN1; SMN2
SCHEMBL6554541 0.84 ALDH1A1 (0.50) ALDH1A1MEN1KMT2ALMNACYP3A4
SCHEMBL18222941 0.84 LTA4H (0.39) ALDH1A1LMNACYP3A4MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2981752-B2 1999-11-22 JP claimed
JP-2981770-B2 1999-11-22 JP claimed
US-5972122-A USED IN ZERO-MERCURY, ZINC AIR ELECTROCHEMICAL CELL; INVOLVES CONTACTING ANODE CUP WITH AQUEOUS DETERSIVE SYSTEM CONTAINING ONE OR MORE SURFACTANTS AND SUBJECTED TO ULTRASONIC FIELD EVEREADY BATTERY COMPANY, INC. (US) 1999-10-26 US claimed
US-5397397-A Method for cleaning and drying of metallic and nonmetallic surfaces CRESTEK, INC. (US) 1995-03-14 US claimed
US-5395570-A Hollow fibre membrane extrusion MEMTEC LIMITED (AU) 1995-03-07 US claimed
EP-0408688-B1 POROUS MEMBRANES MEMTEC LTD (AU) 1994-03-23 EP claimed
US-5277851-A Removing surfactant from polyolefin fiber MEMTEC LIMITED (AU) 1994-01-11 US claimed
EP-0423249-A4 EXTRUSION OF HOLLOW FIBRE MEMBRANES 1991-05-22 EP claimed
EP-0423249-A1 EXTRUSION OF HOLLOW FIBRE MEMBRANES. MEMTEC LTD (AU) 1991-04-24 EP claimed
EP-0408688-A4 POROUS MEMBRANES 1991-04-17 EP claimed
EP-0408688-A1 POROUS MEMBRANES. MEMTEC LTD (AU) 1991-01-23 EP claimed
WO-1990005007-A1 POROUS MEMBRANES MEMTEC LIMITED (AU) 1990-05-17 WO claimed
WO-1990005006-A1 EXTRUSION OF HOLLOW FIBRE MEMBRANES MEMTEC LIMITED (AU) 1990-05-17 WO claimed
EP-0884375-B1 Reaction products of substituted carboxylic acylating agents and carboxylic reactants for use in fuels and lubricants LUBRIZOL CORP (US) 2004-12-29 EP disclosed
US-6818601-B1 REACTION PRODUCT OF HYDROCARBON POLYMER GRAFTED WITH ALPHA,BETA-ETHYLENICALLY UNSATURATED CARBOXYLIC ACID AND AN AMINE THE LUBRIZOL CORPORATION 2004-11-16 US disclosed
EP-0899276-B1 Low chlorine content compositions for use in lubricants and fuels LUBRIZOL CORP (US) 2003-10-29 EP disclosed
EP-0408688-A4 POROUS MEMBRANES 1991-04-17 EP disclosed
EP-0408688-A1 POROUS MEMBRANES. MEMTEC LTD (AU) 1991-01-23 EP disclosed
WO-1990005006-A1 EXTRUSION OF HOLLOW FIBRE MEMBRANES MEMTEC LIMITED (AU) 1990-05-17 WO disclosed
WO-1990005007-A1 POROUS MEMBRANES MEMTEC LIMITED (AU) 1990-05-17 WO disclosed