Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.50 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MLNR | O43193 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6554479 | 0.88 | LTA4H (0.45) | ALDH1A1LMNACYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL11227334 | 0.88 | LTA4H (0.45) | ALDH1A1LMNACYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL7124634 | 0.87 | LTA4H (0.50) | ALDH1A1LMNACYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL28741361 | 0.87 | LTA4H (0.50) | ALDH1A1LMNACYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL6554482 | 0.84 | ALDH1A1 (0.42) | ALDH1A1LMNACYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL330344 | 0.84 | ALDH1A1 (0.42) | ALDH1A1LMNACYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL22574890 | 0.83 | LTA4H (0.47) | ALDH1A1LMNACYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL9053800 | 0.83 | LTA4H (0.49) | ALDH1A1LMNACYP3A4MAPK1SMN1; SMN2 | |
| Phosphoric Acid SCHEMBL11394075 | 0.83 | LPAR1 (0.45) | LTA4HRECQLFAAHTSHR | |
| SCHEMBL4376616 | 0.82 | LTA4H (0.54) | ALDH1A1LMNACYP3A4MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0884375-B1 | Reaction products of substituted carboxylic acylating agents and carboxylic reactants for use in fuels and lubricants | LUBRIZOL CORP (US) | 2004-12-29 | — | — | EP | disclosed |
| US-6818601-B1 | REACTION PRODUCT OF HYDROCARBON POLYMER GRAFTED WITH ALPHA,BETA-ETHYLENICALLY UNSATURATED CARBOXYLIC ACID AND AN AMINE | THE LUBRIZOL CORPORATION | 2004-11-16 | — | — | US | disclosed |
| EP-0899276-B1 | Low chlorine content compositions for use in lubricants and fuels | LUBRIZOL CORP (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6165235-A | Low chlorine content compositions for use in lubricants and fuels | THE LUBRIZOL CORPORATION (US) | 2000-12-26 | — | — | US | disclosed |
| US-5912213-A | REACTION OF OLEFIN WITH CARBOXYLIC REACTANT FOR ACYLATION | THE LUBRIZOL CORPORATION (US) | 1999-06-15 | — | — | US | disclosed |
| EP-0899276-A1 | Low chlorine content compositions for use in lubricants and fuels | The Lubrizol Corporation (US) | 1999-03-03 | — | — | EP | disclosed |
| US-5851966-A | Reaction products of substituted carboxylic acylating agents and carboxylic reactants for use in fuels and lubricants | THE LUBRIZOL CORPORATION (US) | 1998-12-22 | — | — | US | disclosed |
| EP-0884375-A1 | Reaction products of substituted carboxylic acylating agents and carboxylic reactants for use in fuels and lubricants | The Lubrizol Corporation (US) | 1998-12-16 | — | — | EP | disclosed |
| EP-0882783-A2 | Substituted carboxylic acylating agent compositions and derivatives thereof for use in lubricants and fuels | The Lubrizol Corporation (US) | 1998-12-09 | — | — | EP | disclosed |
| EP-0882782-A2 | Nitrogen-containing dispersant-viscosity improvers for lubricating oils | The Lubrizol Corporation (US) | 1998-12-09 | — | — | EP | disclosed |