Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ACACB | O00763 | 15/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6552531 | 0.89 | ESR1 (0.46) | POLBMAPTPKMACACBESR1 | |
| SCHEMBL6554555 | 0.89 | ACACB (0.45) | POLBMAPTPKMACACBESR1 | |
| SCHEMBL6541208 | 0.88 | CNR1 (0.56) | PKMACACBCNR1ALDH1A1 | |
| SCHEMBL6540030 | 0.86 | ACACB (0.47) | ACACBESR1KCNH2CNR1ALDH1A1 | |
| SCHEMBL6540634 | 0.86 | ACACB (0.47) | ACACBESR1KCNH2CNR1ALDH1A1 | |
| SCHEMBL6553983 | 0.85 | KMT2A (0.43) | POLBMAPTPKMACACBESR1 | |
| SCHEMBL6552876 | 0.85 | ESR1 (0.39) | POLBMAPTPKMACACBESR1 | |
| SCHEMBL6540798 | 0.84 | ALDH1A1 (0.56) | ACACBCNR1ALDH1A1LMNAKMT2A | |
| SCHEMBL6541437 | 0.84 | ESR1 (0.46) | ACACBESR1KCNH2CNR1ELANE | |
| SCHEMBL6539913 | 0.84 | ESR1 (0.46) | ACACBESR1KCNH2CNR1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |