Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1404367 | 0.89 | KMT2A (0.41) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9725912 | 0.86 | NQO1 (0.40) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7953637 | 0.86 | MAPK1 (0.40) | MAPK1KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL1569511 | 0.85 | ESR1 (0.39) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7386281 | 0.84 | ALDH1A1 (0.37) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7387017 | 0.84 | TAAR1 (0.39) | MAPK1KDM4ELTA4HPLA2G2A | |
| SCHEMBL7389699 | 0.81 | HTR1B (0.43) | KDM4EALDH1A1MTNR1AMTNR1BLMNA | |
| SCHEMBL7387972 | 0.81 | MAPT (0.41) | KDM4EALDH1A1SMN1; SMN2LTA4H | |
| SCHEMBL677451 | 0.80 | LTA4H (0.43) | NPC1ALDH1A1RAB9AAHRTSHR | |
| SCHEMBL7995906 | 0.80 | CCR1 (0.34) | MAPK1ALDH1A1MTNR1AMTNR1BCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0851857-B1 | INHIBITORS OF TUMOR NECROSIS FACTOR ALPHA | CELGENE CORP (US) | 2004-02-18 | — | — | EP | disclosed |
| US-5219982-A | PROCESS FOR COPOLYMERIZING CO/OLEFIN | SHELL OIL COMPANY (US) | 1993-06-15 | — | — | US | disclosed |