Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SHBG | P04278 | 1/20 | 0.47 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.45 |
| ▸ | ABAT | P80404 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24711215 | 0.86 | MAPK1 (0.50) | CA12CA1CA2CA9MAPK1 | |
| SCHEMBL11811539 | 0.84 | MAPK1 (0.49) | CA12CA1CA2CA9MAPK1 | |
| SCHEMBL69884 | 0.82 | GPR35 (0.65) | CYP3A4HIF1ACA12CA1CA2 | |
| SCHEMBL29666479 | 0.82 | GPR35 (0.65) | CYP3A4HIF1ACA12CA1CA2 | |
| SCHEMBL445240 | 0.82 | ALDH1A1 (0.56) | CYP2D6CA12CA1CA2CA9 | |
| SCHEMBL10385267 | 0.81 | TSHR (0.51) | CYP3A4CYP2D6HIF1AGPR35ALDH1A1 | |
| SCHEMBL4474221 | 0.80 | GPR35 (0.62) | CYP3A4CA12CA1CA2CA9 | |
| SCHEMBL17028799 | 0.80 | GPR35 (0.62) | CYP3A4CA12CA1CA2CA9 | |
| SCHEMBL8375677 | 0.80 | ESR1 (0.58) | CA12CA1CA2CA9MAPK1 | |
| SCHEMBL6554673 | 0.80 | CNR1 (0.50) | MAPK1GPR35TP53SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055567-A | Preparation of o,o'-dihydroxyazobenzenes from o-nitrophenols | PHILLIPS PETROLEUM COMPANY (US) | 1977-10-25 | — | — | US | claimed |
| EP-1016653-B1 | Preparation of high-dye yield couplers and intermediates useful therein | EASTMAN KODAK CO (US) | 2004-02-25 | — | — | EP | disclosed |
| US-6172260-B1 | Preparation of high dye-yield couplers and intermediates useful therein | EASTMAN KODAK COMPANY | 2001-01-09 | — | — | US | disclosed |
| US-6132944-A | A FORMED CARBAMYLOXY GROUP OR A SULFONYLISOCYANATO GROUP LINKED A COUPLER AND A DYE; EXHIBIT A HIGHER REACTIVITY WITH OXIDIZED DEVELOPER | EASTMAN KODAK COMPANY (US) | 2000-10-17 | — | — | US | disclosed |
| EP-1016916-A1 | Photographic element containing high dye-yield couplers | EASTMAN KODAK COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| EP-1016653-A1 | Preparation of high-dye yield couplers and intermediates useful therein | EASTMAN KODAK COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| CN-1258861-A | Photographic element containing high dye productivity colour former | EASTMAN KODAK CO (US) | 2000-07-05 | — | — | CN | disclosed |
| US-4055567-A | Preparation of o,o'-dihydroxyazobenzenes from o-nitrophenols | PHILLIPS PETROLEUM COMPANY (US) | 1977-10-25 | — | — | US | disclosed |