Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.58 |
| ▸ | AR | P10275 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.50 |
| ▸ | ABAT | P80404 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24711215 | 0.88 | MAPK1 (0.50) | ESR1ESR2ARMAPK1GPR35 | |
| SCHEMBL69884 | 0.84 | GPR35 (0.65) | ESR1MAPK1GPR35ALDH1A1TP53 | |
| SCHEMBL29666479 | 0.84 | GPR35 (0.65) | ESR1MAPK1GPR35ALDH1A1TP53 | |
| SCHEMBL445240 | 0.84 | ALDH1A1 (0.56) | MAPK1GPR35ALDH1A1TP53HPGD | |
| SCHEMBL11683508 | 0.83 | MAPK1 (0.45) | ESR1ESR2ARMAPK1GPR35 | |
| SCHEMBL4474221 | 0.82 | GPR35 (0.62) | ESR1ESR2ARMAPK1GPR35 | |
| SCHEMBL17028799 | 0.82 | GPR35 (0.62) | ESR1ESR2ARMAPK1GPR35 | |
| SCHEMBL15540150 | 0.82 | MEN1 (0.50) | ESR1ESR2ARMAPK1GPR35 | |
| SCHEMBL28134105 | 0.81 | ALDH1A1 (0.48) | MAPK1GPR35ALDH1A1TP53HPGD | |
| SCHEMBL6554667 | 0.80 | CYP3A4 (0.51) | ESR1ARMAPK1GPR35ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977413-A | Method for producing bis(3-amino-4-hydroxyphenyl) compounds | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0895985-A2 | Method for producing bis(3-amino-4-hydroxyphenyl) compounds | Nippon Kayaku Kabushiki Kaisha (JP) | 1999-02-10 | — | — | EP | disclosed |