Sugi Predict

Sugi Predict / Compounds / Tyrosine

Tyrosine

Tyrosine

SCHEMBL6554685

C[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O.NCC(=O)O.NCC(=O)O.NCC(=O)O.N[C@@H](CO)C(=O)O.N[C@@H](CS)C(=O)O.N[C@@H](CS)C(=O)O.N[C@@H](Cc1c[nH]cn1)C(=O)O.N[C@@H](Cc1ccc(O)cc1)C(=O)O.O=C(O)[C@@H]1CCCN1.O=C(O)[C@@H]1CCCN1.O=C(O)[C@@H]1CCCN1

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC5A2

The experimentally established mechanism targets of Tyrosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ ITGA4 P13612 5/20 0.33
▸ SLC7A5 Q01650 1/20 0.32
▸ F2 P00734 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL4948067 0.92 SLC7A5 (0.35) ITGA4SLC7A5
Tyrosine SCHEMBL6157198 0.92 SLC7A5 (0.35) ITGA4SLC7A5
Tyrosine SCHEMBL6554735 0.92 SLC7A5 (0.39) ITGA4SLC7A5
Tyrosine SCHEMBL7630915 0.91 SLC7A5 (0.39) ITGA4SLC7A5
Tyrosine SCHEMBL28079282 0.87 SLC7A5 (0.40) ITGA4SLC7A5
Tyrosine SCHEMBL8185595 0.87 F2 (0.35) F2
Tyrosine SCHEMBL6554731 0.87 SLC7A5 (0.36) ITGA4SLC7A5
Tyrosine SCHEMBL6511987 0.87 SLC7A5 (0.36) ITGA4SLC7A5F2
Histidine SCHEMBL29087098 0.86 REN (0.30) —
Histidine SCHEMBL27576520 0.84 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0957111-B1 Specific binding proteins for treating canine allergy IDEXX LAB INC (US) 2004-12-29 — — EP claimed
EP-1082340-A1 PEPTIDE VACCINE FOR CANINE ALLERGY IDEXX LABORATORIES, INC. (US) 2001-03-14 — — EP claimed
WO-2000058349-A1 PEPTIDE VACCINE FOR CANINE ALLERGY IDEXX LABORATORIES, INC. (US) 2000-10-05 — — WO claimed
EP-0955311-A2 Peptide vaccine for canine allergy IDEXX LABORATORIES, INC. (US) 1999-11-10 — — EP claimed
EP-0957111-B1 Specific binding proteins for treating canine allergy IDEXX LAB INC (US) 2004-12-29 — — EP disclosed
US-6734287-B1 SPECIFICALLY BIND TO AN ISOLATED AND PURIFIED PEPTIDE COMPRISING A LEUCINE POSITIONED TWO PEPTIDE BONDS AWAY FROM A TYROSINE-ARGININE PAIR; PROVIDE IMMUNITY TO DOG'S IMMUNOGLOBULIN E MOLECULES IDEXX LABORATORIES, INC. 2004-05-11 — — US disclosed
WO-2000058365-A9 SPECIFIC BINDING PROTEINS FOR TREATING CANINE ALLERGY IDEXX LAB INC (US) 2001-11-15 — — WO disclosed
EP-1082346-A1 SPECIFIC BINDING PROTEINS FOR TREATING CANINE ALLERGY IDEXX LABORATORIES, INC. (US) 2001-03-14 — — EP disclosed
EP-1082340-A1 PEPTIDE VACCINE FOR CANINE ALLERGY IDEXX LABORATORIES, INC. (US) 2001-03-14 — — EP disclosed
WO-2000058349-A1 PEPTIDE VACCINE FOR CANINE ALLERGY IDEXX LABORATORIES, INC. (US) 2000-10-05 — — WO disclosed
WO-2000058365-A1 SPECIFIC BINDING PROTEINS FOR TREATING CANINE ALLERGY IDEXX LABORATORIES, INC. (US) 2000-10-05 — — WO disclosed
EP-0957111-A2 Specific binding proteins for treating canine allergy IDEXX LABORATORIES, INC. (US) 1999-11-17 — — EP disclosed