Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tyrosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 12/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL28368606 | 0.88 | SLC7A5 (0.44) | SLC7A5ITGA4ITGB1REN | |
| Tyrosine SCHEMBL6554685 | 0.87 | ITGA4 (0.33) | SLC7A5ITGA4 | |
| Tyrosine SCHEMBL15676202 | 0.85 | SLC7A5 (0.45) | SLC7A5ITGA4ITGB1 | |
| Tyrosine SCHEMBL3100805 | 0.85 | SLC7A5 (0.56) | SLC7A5ITGA4ITGB1 | |
| Tyrosine SCHEMBL22290100 | 0.85 | SLC7A5 (0.56) | SLC7A5ITGA4ITGB1 | |
| Tyrosine SCHEMBL1675510 | 0.85 | SLC7A5 (0.56) | SLC7A5ITGA4ITGB1 | |
| Tyrosine SCHEMBL6665573 | 0.85 | SLC7A5 (0.56) | SLC7A5ITGA4ITGB1 | |
| Tyrosine SCHEMBL17728298 | 0.85 | SLC7A5 (0.56) | SLC7A5ITGA4ITGB1OPRM1 | |
| Tyrosine SCHEMBL17728297 | 0.85 | SLC7A5 (0.56) | SLC7A5ITGA4ITGB1OPRM1 | |
| Dl-Phenylalanine SCHEMBL28971378 | 0.84 | ANPEP (0.43) | SLC7A5REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105765067-A | Modified beta-galactosidase | 天野酶株式会社 | 2016-07-13 | — | — | CN | claimed |
| CN-105765067-A | Modified beta-galactosidase | 天野酶株式会社 | 2016-07-13 | — | — | CN | disclosed |