Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.44 |
| ▸ | PPARG | P37231 | 7/20 | 0.44 |
| ▸ | PPARD | Q03181 | 7/20 | 0.44 |
| ▸ | PPARA | Q07869 | 7/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27842011 | 0.97 | LMNA (0.48) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL27654619 | 0.97 | LMNA (0.48) | LMNASLC22A6TSHRNFKB1PMP22 | |
| Adipic Acid SCHEMBL3690204 | 0.86 | AKR1B1 (0.62) | LMNASLC22A6TSHRAKR1B1GPR84 | |
| Sebacic Acid SCHEMBL28729977 | 0.84 | GPR84 (0.64) | LMNASLC22A6TSHRAKR1B1GPR84 | |
| SCHEMBL381203 | 0.84 | LMNA (0.50) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL2331455 | 0.83 | — | — | |
| SCHEMBL2427620 | 0.82 | LMNA (0.48) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL7086369 | 0.82 | LMNA (0.48) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL1572851 | 0.81 | LMNA (0.53) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL14359877 | 0.81 | TDP1 (0.54) | LMNASLC22A6TSHRNFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105624127-A | Glucose dehydrogenase and application of glucose dehydrogenase in synthesizing statin drug intermediate | NANJING ABIOCHEM BIOMEDICAL TECH CO LTD | 2016-06-01 | — | — | CN | claimed |
| CN-101528917-B | Compositions and methods for preparing stereoisomerically pure statins and synthetic intermediates thereof | CODEXIS, INC. (US) | 2015-07-29 | — | — | CN | claimed |
| CN-104789505-A | Method and strain for preparing cis-3,5-dihydroxyhexanoate compound by reduction and strain | SUZHOU DONGHESHENGCHANG BIOTECHNOLOGY CO LTD | 2015-07-22 | — | — | CN | claimed |
| CN-117898990-A | Composition containing collagen and sweet wormwood herb extract and application thereof | 上海家化联合股份有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-116277908-B | Biaxial stretching preparation method of high-water-resistance PET protective film | 合肥长阳新材料科技有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-116350558-A | Method for preparing plant humectant from caper fruits and application of plant humectant | 云南贝泰妮生物科技集团股份有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-116277908-A | Biaxial stretching preparation method of high-water-resistance PET protective film | 合肥长阳新材料科技有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-111500599-A | Recombinant polynucleotide sequence for preparing astaxanthin and application thereof | 中央研究院 | 2020-08-07 | — | — | CN | disclosed |
| CN-107261002-B | Traditional Chinese medicine composition for treating hyperlipidemia, preparation method and application thereof | 江苏康缘药业股份有限公司 | 2020-06-05 | — | — | CN | disclosed |
| CN-110016503-A | For instructing the SNP site detection kit and its application method of reducing blood lipid medication | 南京格致医学检验有限公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-108078979-A | For overcoming non-small cell lung cancer EGFR-TKIs drug resistances and scheme of combination drug therapy | 中国药科大学 | 2018-05-29 | — | — | CN | disclosed |
| CN-1537019-A | Medical combination of aldosterone receptor antagonist and HMG CoA reductase inhibitor | �ź㴫 | 2004-10-13 | — | — | CN | disclosed |
| EP-1184380-B1 | Ammonium 3,5,6-trihydroxyhexanoate derivatives and preparation process thereof | TAKASAGO PERFUMERY CO LTD (JP) | 2004-02-25 | — | — | EP | disclosed |
| CN-1452973-A | Orally taken antioxidant and antilipemic medicine | UNIV SHAANXI NORMAL (CN) | 2003-11-05 | — | — | CN | disclosed |
| EP-1077212-B1 | PROCESS FOR PRODUCING 6-CYANOMETHYL-1,3-DIOXANE-4-ACETIC ACID DERIVATIVES | KANEKA CORP (JP) | 2003-08-20 | — | — | EP | disclosed |
| EP-0915866-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF PROTECTED ESTERS OF (S)-3,4-DIHYDROXYBUTYRIC ACID | WARNER-LAMBERT COMPANY (US) | 1999-05-19 | — | — | EP | disclosed |
| EP-0910633-A2 | POLYKETIDES AND THEIR SYNTHESIS | Biotica Technology Limited (GB) | 1999-04-28 | — | — | EP | disclosed |
| WO-1998004543-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF PROTECTED ESTERS OF (S)-3,4-DIHYDROXYBUTYRIC ACID | WARNER-LAMBERT COMPANY (US) | 1998-02-05 | — | — | WO | disclosed |
| WO-1998001546-A2 | POLYKETIDES AND THEIR SYNTHESIS | BIOTICA TECHNOLOGY LIMITED (GB) | 1998-01-15 | — | — | WO | disclosed |
| US-4758475-A | Isocyanate-free polyurethane dispersions | HOECHST AG (DE) | 1988-07-19 | — | — | US | disclosed |