Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.74 |
| ▸ | HPGD | P15428 | 3/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.74 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.74 |
| ▸ | TTR | P02766 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | F2 | P00734 | 3/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TDP2 | O95551 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL29379869 | 1.00 | ALDH1A1 (0.74) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| Sulfuric Acid SCHEMBL9839826 | 1.00 | ALDH1A1 (0.74) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL11407768 | 0.92 | ALDH1A1 (0.68) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL27668914 | 0.88 | ALDH1A1 (0.63) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL10904715 | 0.87 | ALDH1A1 (0.74) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| Trifluoromethanesulfonic Acid SCHEMBL28746942 | 0.87 | ALDH1A1 (0.61) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL28734904 | 0.87 | ALDH1A1 (0.61) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL8911808 | 0.87 | TTR (0.68) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| Sulfuric Acid SCHEMBL8642510 | 0.86 | TTR (0.72) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL4941999 | 0.86 | ALDH1A1 (1.00) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114292213-A | New synthesis process of 1-naphthylamine-4-sodium sulfonate | 洛阳和梦科技有限公司 | 2022-04-08 | — | — | CN | claimed |
| US-4376737-A | Process for the production of naphthylaminehydroxysulphonic acids | CIBA-GEIGY AG (CH) | 1983-03-15 | — | — | US | claimed |
| WO-2023070173-A1 | BIOMARKERS AND USES THEREFOR | GenoDx Pty Ltd (AU) | 2023-05-04 | — | — | WO | disclosed |
| WO-2023073392-A1 | BIOMARKERS AND USES THEREFOR | GENODX (AU) | 2023-05-04 | — | — | WO | disclosed |
| US-20230084261-A1 | EXPANDABLE DEVICE FOR TISSUE COLLECTION FROM AN AERODIGESTIVE BODY LUMEN | ADN INTERNATIONAL, LLC (US) | 2023-03-16 | — | — | US | disclosed |
| US-20220185860-A1 | CELL SURFACE COUPLING OF NANOPARTICLES | IRVINE, DARRELL | 2022-06-16 | — | — | US | disclosed |
| CN-114292213-A | New synthesis process of 1-naphthylamine-4-sodium sulfonate | 洛阳和梦科技有限公司 | 2022-04-08 | — | — | CN | disclosed |
| US-11261226-B2 | Cell surface coupling of nanoparticles | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (MITN1) (US) | 2022-03-01 | — | — | US | disclosed |
| US-20220016127-A1 | COMPOSITIONS AND METHODS FOR INDUCING APPENDAGE AND LIMB REGENERATION | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2022-01-20 | — | — | US | disclosed |
| EP-3936122-A1 | METHODS AND COMPOSITIONS FOR LOCALIZED AGENT DELIVERY | Massachusetts Institute Of Technology (US) | 2022-01-12 | — | — | EP | disclosed |
| US-11034752-B2 | Cell surface coupling of nanoparticles | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-06-15 | — | — | US | disclosed |
| WO-2004004661-A2 | BOROPROLINE COMPOUND COMBINATION THERAPY | POINT THERAPEUTICS, INC. (US) | 2004-01-15 | — | — | WO | disclosed |
| WO-2004004658-A2 | METHODS AND COMPOSITIONS RELATING TO ISOLEUCINE BOROPROLINE COMPOUNDS | POINT THERAPEUTICS, INC. (US) | 2004-01-15 | — | — | WO | disclosed |
| WO-1994013277-A2 | USE OF DINAPHTHALENES COMPOUNDS AS ANTIPROLIFERATIVE AGENTS | IMPERIAL CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |
| EP-0214544-B1 | PROCESS FOR THE PREPARATION OF 1-AMINO-NAPHTHALENE 4-SULFONIC ACID (NAPHTHIONIC ACID) | BAYER AG (DE) | 1991-06-19 | — | — | EP | disclosed |
| EP-0131542-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1989-04-19 | — | — | EP | disclosed |
| EP-0131542-A1 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1985-01-16 | — | — | EP | disclosed |
| US-4376737-A | Process for the production of naphthylaminehydroxysulphonic acids | CIBA-GEIGY AG (CH) | 1983-03-15 | — | — | US | disclosed |
| US-4376737-A | Process for the production of naphthylaminehydroxysulphonic acids | CIBA-GEIGY AG (CH) | 1983-03-15 | — | — | US | disclosed |
| US-4376737-A | Process for the production of naphthylaminehydroxysulphonic acids | CIBA-GEIGY AG (CH) | 1983-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220185860-A1 | CELL SURFACE COUPLING OF NANOPARTICLES | EPCAM, CD47, CD63 | ALDH1A1 3199/4885CYP3A4 4834/4885HPGD 4739/4885 |
| US-11034752-B2 | Cell surface coupling of nanoparticles | EPCAM, CD47, CD63 | ALDH1A1 3199/4885CYP3A4 4834/4885HPGD 4739/4885 |
| US-11261226-B2 | Cell surface coupling of nanoparticles | EPCAM, CD47, CD63 | ALDH1A1 3199/4885CYP3A4 4834/4885HPGD 4739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.