SCHEMBL6555091

SCHEMBL6555091

CC(C)(C)OC(=O)N1CCC(Oc2ccc(C(=O)NCCOc3cc(C#N)ccc3C=COP(=O)(O)O)cc2)CC1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 5/20 0.50
F10 P00742 3/20 0.43
F2 P00734 1/20 0.42
ALK Q9UM73 1/20 0.41
CHEK2 O96017 1/20 0.40
CCNC P24863 1/20 0.39
CDK8 P49336 1/20 0.39
HDAC1 Q13547 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
IRAK4 Q9NWZ3 1/20 0.38
CETP P11597 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6873900 0.89 GPR119 (0.51) GPR119F10F2ALKCHEK2
SCHEMBL6873899 0.89 GPR119 (0.51) GPR119F10F2ALKCHEK2
SCHEMBL6864795 0.87 GPR119 (0.51) GPR119F10F2ALKCHEK2
SCHEMBL6864800 0.87 GPR119 (0.51) GPR119F10F2ALKCHEK2
SCHEMBL3897950 0.85 GPR119 (0.56) GPR119F10F2ALKHDAC1
SCHEMBL3899273 0.83 GPR119 (0.48) GPR119F10F2ALKCHEK2
SCHEMBL3899270 0.83 GPR119 (0.48) GPR119F10F2ALKCHEK2
SCHEMBL6874416 0.81 GPR119 (0.52) GPR119F10F2ALK
SCHEMBL3912286 0.81 F10 (0.60) GPR119F10F2ALKL3MBTL1
SCHEMBL6555353 0.79 CA12 (0.40) CCNCCDK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6784191-B2 AS BLOOD-COAGULATION INHIBITOR OR AN AGENT FOR THERAPY AND PROPHYLAXIS OF THROMBOSIS OR EMBOLISM, CONTAINING AJINOMOTO CO., INC. (JP) 2004-08-31 US disclosed
EP-1236735-B1 BENZAMIDINE DERIVATIVES AJINOMOTO KK (JP) 2004-02-25 EP disclosed
US-20020193348-A1 Benzamidine derivatives AJINOMOTO CO., INC. (JP) 2002-12-19 US disclosed
EP-1236735-A1 BENZAMIDINE DERIVATIVES Ajinomoto Co., Inc. (JP) 2002-09-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020193348-A1 Benzamidine derivatives SERPINC1, SERPINE1, TFPI GPR119 3944/4885F10 14/4885F2 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.