Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28794452 | 0.99 | HTT (0.60) | HTTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL20522035 | 0.86 | HTT (0.60) | HTTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL28347687 | 0.79 | KMT2A (0.64) | HTTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL31497191 | 0.79 | KMT2A (0.64) | HTTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL2961298 | 0.77 | ALDH1A1 (0.48) | MEN1KMT2AKDM4EMAPT | |
| SCHEMBL3981991 | 0.76 | GCGR (0.69) | MAPT | |
| SCHEMBL3979045 | 0.76 | GCGR (0.73) | SMN1; SMN2 | |
| SCHEMBL11654108 | 0.75 | CASP6 (0.67) | HTTMEN1KMT2AMAPT | |
| SCHEMBL3978229 | 0.74 | GCGR (0.63) | — | |
| SCHEMBL3974772 | 0.73 | GCGR (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1489077-A1 | 2-FURANCARBOXYLIC ACID HYDRAZIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2004-12-22 | — | — | EP | claimed |