Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17924581 | 0.72 | SMN1; SMN2 (0.54) | ALDH1A1KDM4EABCG2HSD17B10CYP3A4 | |
| SCHEMBL13180056 | 0.70 | CYP19A1 (0.43) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL14684667 | 0.69 | NR1H4 (0.43) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL12523115 | 0.68 | CYP3A4 (0.53) | ALDH1A1KDM4EABCG2HSD17B10CYP3A4 | |
| SCHEMBL17930308 | 0.66 | MAPT (0.49) | ALDH1A1KDM4EABCG2HSD17B10CYP3A4 | |
| SCHEMBL7227639 | 0.65 | SMN1; SMN2 (0.48) | ALDH1A1KDM4EABCG2HSD17B10CYP3A4 | |
| SCHEMBL5103477 | 0.65 | ABCG2 (0.49) | ALDH1A1KDM4EABCG2HSD17B10CYP3A4 | |
| SCHEMBL5707776 | 0.64 | ABCG2 (0.75) | ALDH1A1KDM4EABCG2HSD17B10CYP3A4 | |
| SCHEMBL5707781 | 0.64 | ABCG2 (0.75) | ALDH1A1KDM4EABCG2HSD17B10CYP3A4 | |
| SCHEMBL17973515 | 0.64 | ABCG2 (0.37) | ALDH1A1KDM4EABCG2HSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1489142-A1 | Cationic dyes, method for the production thereof and colourants containing said compounds | Wella Aktiengesellschaft (DE) | 2004-12-22 | — | — | EP | claimed |
| EP-1404289-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | Wella Aktiengesellschaft (DE) | 2004-04-07 | — | — | EP | claimed |
| EP-1397435-A1 | CATIONIC DYES, METHOD FOR THE PRODUCTION THEREOF AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2004-03-17 | — | — | EP | claimed |
| US-20040039202-A1 | Cationic dyes, method for the production thereof, and colouring agents containing said compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2004-02-26 | — | — | US | claimed |
| US-20030196281-A1 | 1-benzopyrane-derivatives and colouring agents containing the salts thereof | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | US | claimed |
| WO-2003000799-A1 | CATIONIC DYES, METHOD FOR THE PRODUCTION THEREOF AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2003-01-03 | — | — | WO | claimed |
| WO-2003000214-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | WELLA AKTIENGESELLSCHAFT (DE) | 2003-01-03 | — | — | WO | claimed |
| EP-1489142-A1 | Cationic dyes, method for the production thereof and colourants containing said compounds | Wella Aktiengesellschaft (DE) | 2004-12-22 | — | — | EP | disclosed |
| EP-1404289-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | Wella Aktiengesellschaft (DE) | 2004-04-07 | — | — | EP | disclosed |
| EP-1397435-A1 | CATIONIC DYES, METHOD FOR THE PRODUCTION THEREOF AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-20040039202-A1 | Cationic dyes, method for the production thereof, and colouring agents containing said compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2004-02-26 | — | — | US | disclosed |
| US-20030196281-A1 | 1-benzopyrane-derivatives and colouring agents containing the salts thereof | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | US | disclosed |
| WO-2003000799-A1 | CATIONIC DYES, METHOD FOR THE PRODUCTION THEREOF AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2003-01-03 | — | — | WO | disclosed |
| WO-2003000214-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | WELLA AKTIENGESELLSCHAFT (DE) | 2003-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040039202-A1 | Cationic dyes, method for the production thereof, and colouring agents containing said compounds | TYR, MPO, NISCH | ALDH1A1 646/4885KDM4E 2777/4885ABCG2 990/4885 |
| US-20030196281-A1 | 1-benzopyrane-derivatives and colouring agents containing the salts thereof | KRT18, COL2A1, PHB1 | ALDH1A1 9/4885KDM4E 3406/4885ABCG2 2980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.