Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4EBP1 | Q13541 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555761 | 0.92 | EIF4EBP1 (0.52) | EIF4EBP1TSHRALDH1A1HPGDMAPK1 | |
| SCHEMBL6557890 | 0.90 | ALDH1A1 (0.44) | EIF4EBP1ALDH1A1HPGDMAPK1KDM4E | |
| SCHEMBL6555851 | 0.81 | MAPT (0.47) | EIF4EBP1ALDH1A1HPGDMAPK1KDM4E | |
| SCHEMBL6557322 | 0.81 | KDM4E (0.52) | TSHRALDH1A1KDM4EKMT2AMAPT | |
| SCHEMBL7013161 | 0.81 | EIF4EBP1 (0.48) | EIF4EBP1TSHRALDH1A1HPGDMAPK1 | |
| SCHEMBL6858495 | 0.77 | EIF4EBP1 (0.49) | EIF4EBP1TSHRALDH1A1HPGDMAPK1 | |
| SCHEMBL6555774 | 0.74 | RAB9A (0.61) | EIF4EBP1ALDH1A1HPGDMAPK1LMNA | |
| SCHEMBL6858494 | 0.73 | EIF4EBP1 (0.49) | EIF4EBP1TSHRALDH1A1HPGDMAPK1 | |
| SCHEMBL6557964 | 0.73 | ACKR3 (0.52) | TSHRALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL15547765 | 0.72 | ELANE (0.46) | TSHRALDH1A1KDM4ELMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073643-B1 | NEW HETEROCYCLIC COMPOUNDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | REDDYS LAB LTD DR (IN) | 2004-12-29 | — | — | EP | disclosed |
| EP-1073643-A2 | NEW HETEROCYCLIC COMPOUNDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999008501-A2 | NEW HETEROCYCLIC COMPOUNDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-02-25 | — | — | WO | disclosed |